Results 11 to 20 of about 179,733 (197)

HPA-CNS model nominal parameter values and sensitivities.

open access: yes, 2023
HPA-CNS model nominal parameter values and sensitivities.
Ben Ron Mizrachi (17593079)   +6 more
core   +1 more source

Clinical characteristics of human platelet antigen (HPA)-1a and HPA-5b alloimmunised pregnancies and the association between platelet HPA-5b antibodies and symptomatic fetal neonatal alloimmune thrombocytopenia [PDF]

open access: yes, 2021
Fetal neonatal alloimmune thrombocytopenia (FNAIT) is caused by maternal alloantibodies directed against the human platelet antigens (mostly HPA-1a or HPA-5b) of the (unborn) child and can lead to severe bleeding.
Winkelhorst, D.   +26 more
core   +1 more source

DataSheet_1_In vitro analysis of anti-HPA-1a dependent platelet phagocytosis and its inhibition using a new whole blood phagocytosis assay (WHOPPA).pdf

open access: yes, 2023
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a serious bleeding condition mostly caused by the reaction between maternal anti-HPA-1a antibodies and fetal platelets. This reaction leads to Fc-dependent platelet phagocytosis.
Gabriela Michel (13410095)   +10 more
core   +1 more source

Human platelet antigen (HPA)-1a alloimmunization - Why only blame it on the platelets? [PDF]

open access: yes, 2021
Antibodies against human platelet antigen (HPA)-1a are the most common cause of fetal and neonatal alloimmune thrombocytopenia (FNAIT) in Caucasians, and is a break of the tolerance normally seen for the fetus in pregnant women.
Heide, Gøril
core   +1 more source

DataSheet_1_Cellular surface plasmon resonance-based detection of anti-HPA-1a antibody glycosylation in fetal and neonatal alloimmune thrombocytopenia.pdf

open access: yes, 2023
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) can occur due to maternal IgG antibodies targeting platelet antigens, causing life-threatening bleeding in the neonate.
Myrthe E. Sonneveld (17100031)   +14 more
core   +1 more source

Serum Heparanase: A New Clinical Biomarker Involved in Senile Metabolic Inflammatory Syndrome

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2021
Qingsong Wang,1 Xiu-ling Zhou,2 Guang-hai Mei,3 Jiantao Wang,1 Zhongyu Yu,1 Yue Hu,1 Xinyu Guo,1 Hanyu Zhang,1 Xiaodie Xu,4 Chengfeng He,4 Jingchun Guo,4 Yinghong Tao,5 Houguang Zhou1 1Department of Geriatrics, Huashan Hospital, National Clinical ...
Zhou X   +12 more
doaj  

Platelet transfusion refractoriness in patients with acute myeloid leukemia: The role of anti-platelet antibodies [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo
Introduction/Objective. Platelet transfusion refractoriness represents a common issue in the treatment course of acute myeloid leukemia (AML) patients who require chronic transfusion support.
Đunić Irena   +3 more
doaj   +1 more source

Establishment of platelet donor gene bank involving specific antigen HPA 1-6/10/15/21 by real-time fluorescent PCR

open access: yesZhongguo shuxue zazhi, 2023
Objective To research the genetic polymorphism of HPA 1-6/10/15/21 in platelet donors in Zhongshan area, and establish a gene bank of platelet donors with HPA locus.
Wensheng YUAN   +5 more
doaj   +1 more source

Genetic polymorphisms of human platelet antigens in Euro-African and Japanese descendants from Parana, Southern Brazil

open access: yesPlatelets, 2017
The frequency distributions of HPA-1 to HPA-6 and HPA-15 were evaluated in two Brazilian populations from Parana: a mixed population of predominantly Caucasians and a population of Japanese descendants.
Ana Paula Avenia Silvestre   +4 more
doaj   +1 more source

Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats [PDF]

open access: yes, 2014
Copyright @ 2013 The authors. This work is licensed under a Creative Commons Attribution 3.0 Unported License.Obesity is a risk factor for sepsis morbidity and mortality, whereas the hypothalamic-pituitary-adrenal (HPA) axis plays a protective role in ...
Bloom, SR   +5 more
core   +1 more source

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