Results 91 to 100 of about 339,718 (373)
U.S. East Coast Trough Indices at 500 hPa and New England Winter Climate Variability [PDF]
, 2002 Using monthly gridded 500-hPa data, two synoptic indices are defined to better understand the principle mechanisms controlling intraseasonal to multiannual winter climate variability in NewEngland (NE).
Bradbury, James A +2 more
core +2 more sources
Advanced Science, EarlyView.A new zinc hybrid guanidine catalyst [Zn{(R,R)TMGNMe2(1,2)ch}2](OTf)2 (C1) shows very high catalytic activity in the polymerization of cyclic esters and in the depolymerization of these polyesters. Using C1 in the ring‐opening polymerization of lactide and caprolactone under industrially relevant conditions, astonishing rate constants of the same order
Tabea Becker +8 more
wiley +1 more source
Frequency of H.Pylory BabA2 and Hpa Genes in Patients with Dysphagia
Medical Laboratory Journal, 2015 Background and Objective: BabA2 and Hpa genes are involved in adherence of Helicobacter pylori (H.pylori) to gastric mucosal tissue. This study aimed to investigate the frequency of these genes in isolates of H.
Khatoon Heydari +4 more
doaj
Association between Stress and the HPA Axis in the Atopic Dermatitis
International Journal of Molecular Sciences, 2017 The hypothalamic–pituitary–adrenal (HPA) axis is one of the body’s neuroendocrine networks that responds to psychological stress (PS). In the skin, there exists a peripheral HPA axis similar to the central axis.
Tzu-Kai Lin, Lily Zhong, J. Santiago
semanticscholar +1 more source
Interdecadal variability of winter precipitation in Southeast China [PDF]
, 2014 Interdecadal variability of observed winter precipitation in Southeast China (1961–2010) is characterized by the first empirical orthogonal function of the three-monthly Standardized Precipitation Index (SPI) subjected to a 9-year running mean.
Fraedrich, K. +4 more
core +1 more source
Advanced Science, EarlyView.Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu +14 more
wiley +1 more source
Understanding vulnerability for depression from a cognitive neuroscience perspective: a reappraisal of attentional factors and a new conceptual framework [PDF]
, 2010 We propose a framework to understand increases in vulnerability for depression after recurrent episodes that links attention processes and schema activation to negative mood states, by integrating cognitive and neurobiological findings.
De Raedt, Rudi, Koster, Ernst
core +1 more source
The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
Advanced Science, EarlyView.The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
Public health and economic costs of investigating a suspected outbreak of Legionnaires' disease. [PDF]
, 2007 This paper provides one of the first assessments of the burden of both the public health investigation and the economic costs associated with an apparent outbreak of Legionnaires' disease (LD) in South East London.
Harrison, TG +8 more
core +2 more sources
Advanced Science, EarlyView.This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu +11 more
wiley +1 more source