Results 101 to 110 of about 158,485 (298)

Chaihu-Shugan-San Ameliorated Osteoporosis of Mice with Depressive Behavior Caused by Chronic Unpredictable Mild Stress via Repressing Neuroinflammation and HPA Activity

Drug Design, Development and Therapy
Ming-Chao He,1,2,* Shi-Hui Xia,2,3,* Hao Pan,4,* Ting-Ting Zhou,5 Xin-Luan Wang,6 Ji-Ming Li,6 Xiao-Ming Li,5 Yan Zhang2,3 1Department of Pain Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People’s ...
He MC, Xia SH, Pan H, Zhou TT, Wang XL, Li JM, Li XM, Zhang Y   +7 more
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Cortisol reactivity to psychosocial stress is greater in sexual risk takers

, 2013
Several studies have reported an association between deviant behaviour and cortisol reactivity to stress. However relatively few studies have investigated the relationship between psychobiological stress reactivity and sexual risk taking behaviours.
Harrison, Claire, Melanie Mitchell, Michael A. Smith, Ratcliffe, Joanne, Mitchell, Melanie, Claire Harrison, Smith, Michael, Joanne M. Ratcliffe   +7 more
core   +1 more source

Anti-human platelet antigen (HPA)-1a antibodies may affect trophoblast functions crucial for placental development: A laboratory study using an in vitro model [PDF]

, 2017
Background: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a bleeding disorder caused by maternal antibodies against paternal human platelet antigens (HPAs) on fetal platelets.
Zhou, Yan, Eksteen, Mariana, Tor B. Stuge, Martinez-Zubiaurre, Inigo, Mariana Eksteen, Nedberg, Nora Hersoug, Heide, Gøril, Yan Zhou, Kjær, Mette, Nora Hersoug Nedberg, Mette Kjær, Husebekk, Anne, Bjørn R. Skogen, Tiller, Heidi, Anne Husebekk, Heidi Tiller, Stuge, Tor Brynjar, Inigo Martinez-Zubiaurre, Gøril Heide, Skogen, Bjørn Ragnar   +19 more
core   +1 more source

Rare‐Earth Mediated Engineering in ZnSe@ZnS:Eu3+ to Simultaneously Achieve Structural Modulation and Atomic Eu Doping Sites for X‐Ray Imaging

Advanced Science, EarlyView.
A dual hard‐base anchoring strategy was developed to synthesize ZnSe@ZnS:Eu3+ quantum dots, leveraging fluoride‐oleylamine interactions to create surface atomic Eu doping sites. By precisely tuning temperature, Eu3+ concentration, and fluoride levels, we obtain morphologies ranging from tip growth to coupled flower‐like structures.
Jicun Ma, Chenhao Yang, Jiada Fan, Haorong Jiao, Jiawang Liu, Jialiang Xu, Hui Cai, Yinghui Wang, Boyuan Shen, Jiabin Cui   +9 more
wiley   +1 more source

Análise da ocorrência dos fluxos e Jatos de Nível Baixo no perfil vertical do vento na baixa atmosfera em Manaus (AM) Analysis of the occurrence of streams and Low Level Jets in the vertical wind profile at the lower-atmosphere of Manaus city

Revista Brasileira de Meteorologia, 2008
Este estudo apresenta uma análise sobre as estruturas verticais nos baixos níveis da atmosfera tropical, região norte do Brasil, utilizando dados de radiossondagem realizadas na cidade de Manaus.
Cleber Souza Corrêa, Flavio Wiegand, Ricardo Dallarosa, Renato Cruz Senna   +3 more
doaj   +1 more source

Familial longevity is marked by lower diurnal salivary cortisol levels: the leiden longevity study [PDF]

, 2012
Background Reported findings are inconsistent whether hypothalamic-pituitary-adrenal (HPA) signaling becomes hyperactive with increasing age, resulting in increasing levels of cortisol.
Westendorp, Rudi G J, Oei Nicole Y. L., Maier, Andrea B., Jansen, Steffy W M, Maier, A.B., de Craen, Anton J M, Akintola, Abimbola A., Pijl Hanno, Noordam, Raymond, Slagboom, P. Eline, Hanno Pijl, Diana van Heemst, Raymond Noordam, Jansen, SWM, Westendorp, RGJ, van der Grond Jeroen, Westendorp Rudi G. J., van Heemst, Diana, P Eline Slagboom, Noordam, R., Steffy W M Jansen, Heemst, D. van, Leiden Longevity Study group, Craen, A.J.M. de, van der Grond, J, Oei, Nicole YL, Jeroen van der Grond, van Heemst Diana, Anton J M de Craen, de Craen Anton J. M., Jansen, S.W.M., van Heemst, D, Noordam, R, de Craen, AJM, Akintola Abimbola A., Grond, J. van der, Pijl, Hanno, Oei, N.Y.L., Maier, Andrea B.; id_orcid, Rudi G J Westendorp, Maier, AB, Maier Andrea B., Pijl, H., Leiden Longevity Study Grp, Slagboom, PE, Noordam Raymond, Nicole Y L Oei, Jansen, Steffy, Slagboom, P.E., de Craen, Anton JM, Oei, Nicole Y L, Andrea B Maier, Jansen Steffy W. M., Oei, NYL, Westendorp, R.G.J., van der Grond, Jeroen, Akintola, Abimbola A, Abimbola A Akintola, Slagboom P. Eline, Akintola, A.A., Akintola, AA, Maier, Andrea B, Westerndorp, Rudi GJ, Pijl, H   +63 more
core   +1 more source

PRMT9 Aggravated Dopaminergic Neurodegeneration in Parkinson's Disease Model by Facilitating the Degradation of DUSP26 and Inducing Mitochondrial Dysfunction

Advanced Science, EarlyView.
In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu, Xiaomeng Song, Xin Guo, Rui Xiao, Ru Sun, Qiuran Ji, Lu Yu, Yiquan Li, Qingyi Fu, Qidi Xue, Lingjun Kong, Lin Chen, Chengjiang Gao, Huiqing Liu   +13 more
wiley   +1 more source

长春地区无偿献血者HPA1-6,15基因分型及频率调查

Zhongguo shiyan zhenduanxue, 2011
目的调查北方汉族人群人类血小板抗原（HPA）的基因频率及分布规律。建立一支HPA-1a,-2a,-4a,-5a,-6a阴性及已知HPA抗原的献血者队伍。方法随机抽取172名长春地区固定无偿血小板捐献者静脉血3ml,枸橼酸钠抗凝;采用TIANGEN试剂盒提取DNA。基因定量仪测定DNA的浓度和纯度。采用PCR-SSP方法进行试验。最后进行统计学分析。结果各表现型的频率分别是:HPA-1aa 0.988,HPA-1ab 0.012,HPA-2aa 0.833,HPA-2ab 0.159,HPA-2bb 0 ...
于江虹, 杨帆, 焦立新, 刘铁梅
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Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

吉林地区人群HPA-1～6,15系统基因多态性分析

Zhongguo shiyan zhenduanxue, 2016
目的调查吉林地区人群人类血小板抗原（HPA）基因多态性。方法采用PCR-SSP方法对419名血小板捐献志愿者进行血小板抗原HPA-16,15系统基因分型,通过统计方法对分型结果进行基因多态性分析。结果血小板抗原HPA-16,15系统基因频率分别为HPA-1aa 0.984,HPA-1ab 0.016,HPA-2aa 0.872,HPA-2ab 0.123,HPA-2bb 0.004,HPA-3aa 0.350,HPA-3ab 0.483,HPA-3bb 0.166,HPA-4aa 0.992,HPA ...
杨帆, 韩瑜, 焦立新, 鲁威, 金成日, 陈琳, 牛潼, 李俊玮   +7 more
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