Results 121 to 130 of about 174,417 (293)

Glucocorticoid exposure and initiation of SSRIs among patients with rheumatoid arthritis: A nested case–control study in UK primary care

British Journal of Clinical Pharmacology, EarlyView.
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen, Patrick C. Souverein, Eibert R. Heerdink, Elisabeth Y. Bijlsma, Lucianne Groenink   +4 more
wiley   +1 more source

Dose‐related propofol resistance in COVID‐19 patients: Altered drug plasma levels, mechanistic insights from neuronal‐derived extracellular vesicles and miRNA analysis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Critical care for COVID‐19 patients presents unique challenges, particularly in sedation management. Patients demonstrate notable dose‐related resistance to propofol, potentially due to complex pharmacokinetic alterations. Emerging evidence suggests that plasma extracellular vesicle‐associated miRNA represents valuable predictive ...
Debora Curci, Carlotta Bidoli, Marco Gerdol, Charisse Winston, Robert A. Rissman, Giuliana Decorti, Antonella Fabretto, Andrea Taddio, Gabriele Stocco, Erik Roman‐Pognuz, Marianna Lucafò   +10 more
wiley   +1 more source

Gene frequency and distribution of human platelet antigen-1 to −6, −10, −15, and −21 of platelets donors in Wuhan, China

Global Medical Genetics
Background: In this study, the frequency of human platelet antigen (HPA) alleles and genotypes of platelet donors in Wuhan was evaluated and differences in HPA distribution between Wuhan and other regions in China were compared. Study Design and Methods:
Zhen Qu, Wangxia Li, Yuanyan Zhu, Xue Zheng, Mingdi He, Gang Shen, Anyu Bao   +6 more
doaj   +1 more source

Diurnal Variation in Peripheral (Hair) vs Central (Saliva) HPA Axis Cortisol Concentrations

, 2010
Cortisol concentrations in hair and saliva collected from male and female adults over a 15-hour period were compared for differences in overall level and cyclic pattern.
Kauter, Kathleen G., Kathleen G. Kauter, Sharpley, Christopher F., Sharpley, Christopher F, Christopher F. Sharpley, McFarlane, James R., Kauter, Kathleen G, James R. Mcfarlane, McFarlane, James R   +8 more
core   +1 more source

Expanding Metabolic Online Monitoring Capabilities in 96‐Deepwell Microtiter Plates by Combining Optoelectronic O2 and CO2 Sensors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT To increase the information content in early stages of bioprocess development, various technologies have been introduced for monitoring cultivations in microtiter plates (MTPs). Besides spectroscopical measurements, like in the BioLector technology, optical measurements with luminescent sensors, placed directly in the cultivation medium ...
Robert Dinger, David Pfeifer, David Flitsch, Jan P. Fischer, Clemens Lattermann, Sergey M. Borisov, Jochen Büchs   +6 more
wiley   +1 more source

Development of Physics Applied to Medicine in the UK, 1945–90, vol. 28. [PDF]

, 2006
Organized with the assistance of Professor John Clifton (UCL) and chaired by Professor Peter Williams (Manchester), this seminar examined the early developments of medical physics in the UK between 1945 and 1990.

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Stress, the hippocampus and the HPA axis: Implications for the development of psychotic disorders

, 2006
The experience of stress is commonly implicated in models of the onset of psychotic disorders. However, prospective studies investigating associations between biological markers of stress and the emergence of psychotic disorders are limited and ...
Katherine N. Thompson, Berger, Gregor, Gregor Berger, Wood, Stephen J., Pantelis, Christos, Phillips, Lisa J., Belinda Garner, Thompson, Kathrine N., Christos Pantelis, Garner, Belinda, Lisa J. Phillips, Stephen J. Wood, McGorry, Patrick D., Patrick D. Mcgorry   +13 more
core   +1 more source

How developmental stressors affect mitochondrial respiratory function: a systematic review and meta‐analysis

Biological Reviews, EarlyView.
ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino, Christopher R. Friesen, Geoffrey E. Hill, Dalton C. Leibold, Pablo Recio, Karine Salin, Kristoffer H. Wild, Daniel W.A. Noble   +7 more
wiley   +1 more source

Anticipatory Stress in Medical Students Before Their First Cadaver Experience: A Physiological Component of Cadaver‐Based Anatomy Education

Clinical Anatomy, EarlyView.
ABSTRACT Cadaver‐based anatomy education represents a unique biological and sensory experience that may elicit significant physiological responses. However, little is known about the anticipatory phase prior to initial exposure, particularly when evaluated using objective biomarkers.
María Resino‐Rocha, Franscisco Gómez‐Esquer, Cecilia Peñacoba, Antonio Gil‐Crujera, Stella Maris Gómez‐Sánchez, Gema Díaz‐Gil   +5 more
wiley   +1 more source

Immunomodulation by diet : individual differences in sensitivity in layer hens [PDF]

, 2009
Enhancing relevant immunity of production animals to achieve more robust animals is receiving more and more attention. Several epidemics have hit production animals recently and with devastating consequences, but enhancing diseases resistance ...
Adriaansen-Tennekes, R.
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