Results 141 to 150 of about 339,718 (373)

Análise da ocorrência dos fluxos e Jatos de Nível Baixo no perfil vertical do vento na baixa atmosfera em Manaus (AM) Analysis of the occurrence of streams and Low Level Jets in the vertical wind profile at the lower-atmosphere of Manaus city

Revista Brasileira de Meteorologia, 2008
Este estudo apresenta uma análise sobre as estruturas verticais nos baixos níveis da atmosfera tropical, região norte do Brasil, utilizando dados de radiossondagem realizadas na cidade de Manaus.
Cleber Souza Corrêa, Flavio Wiegand, Ricardo Dallarosa, Renato Cruz Senna   +3 more
doaj   +1 more source

Autosomal Dominant Erythrocytosis Caused by Non‐Renal Erythropoietin (EPO) Due to EPO c.‐136 G>A Germline Mutation

American Journal of Hematology, EarlyView.
A novel erythropoietin (EPO) promoter mutation (c.‐136 G>A) causes autosomal dominant erythrocytosis via non‐renal expression of EPO. ABSTRACT We previously reported a five‐generation kindred with autosomal dominant erythrocytosis associated with a novel germline promoter variant in the erythropoietin (EPO) gene (EPO c.‐136 G>A).
Lucie Lanikova, Dusan Hrckulak, Veronika Zimolova, Felipe R. Lorenzo, Jihyun Song, Katerina Vecerkova, Olga Babosova, Linda Berkova, Vladimir Korinek, Steve Elliott, Josef T. Prchal   +10 more
wiley   +1 more source

长春地区无偿献血者HPA1-6,15基因分型及频率调查

Zhongguo shiyan zhenduanxue, 2011
目的调查北方汉族人群人类血小板抗原（HPA）的基因频率及分布规律。建立一支HPA-1a,-2a,-4a,-5a,-6a阴性及已知HPA抗原的献血者队伍。方法随机抽取172名长春地区固定无偿血小板捐献者静脉血3ml,枸橼酸钠抗凝;采用TIANGEN试剂盒提取DNA。基因定量仪测定DNA的浓度和纯度。采用PCR-SSP方法进行试验。最后进行统计学分析。结果各表现型的频率分别是:HPA-1aa 0.988,HPA-1ab 0.012,HPA-2aa 0.833,HPA-2ab 0.159,HPA-2bb 0 ...
于江虹, 杨帆, 焦立新, 刘铁梅
doaj  

Analysis of platelet membrane glycoprotein polymorphisms in Glanzmann thrombasthenia showed the French gypsy mutation in the αIIb gene to be strongly linked to the HPA-1b polymorphism in β3 [PDF]

, 2003
Béatrice Jacquelin, E. Tuleja, Thomas J. Kunicki, Paquita Nurden, Alan T. Nurden   +4 more
openalex   +1 more source

Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source

吉林地区人群HPA-1～6,15系统基因多态性分析

Zhongguo shiyan zhenduanxue, 2016
目的调查吉林地区人群人类血小板抗原（HPA）基因多态性。方法采用PCR-SSP方法对419名血小板捐献志愿者进行血小板抗原HPA-16,15系统基因分型,通过统计方法对分型结果进行基因多态性分析。结果血小板抗原HPA-16,15系统基因频率分别为HPA-1aa 0.984,HPA-1ab 0.016,HPA-2aa 0.872,HPA-2ab 0.123,HPA-2bb 0.004,HPA-3aa 0.350,HPA-3ab 0.483,HPA-3bb 0.166,HPA-4aa 0.992,HPA ...
杨帆, 韩瑜, 焦立新, 鲁威, 金成日, 陈琳, 牛潼, 李俊玮   +7 more
doaj  

Hyaloperonospora arabidopsidis (Downy Mildew) Infection Assay in Arabidopsis

Bio-Protocol, 2015
Hyaloperonospora arabidopsidis (Hpa; formerly Peronospora parasitica or Hyaloperonospora parasitica) is an oomycete downy mildew pathogen of the model plant Arabidopsis.
Shuta Asai, Ken Shirasu, Jonathan Jones
doaj   +1 more source

Skeletal Muscle Biomarkers of Amyotrophic Lateral Sclerosis: A Large‐Scale, Multi‐Cohort Proteomic Study

Annals of Neurology, EarlyView.
Objective Biomarkers with clear contexts of use are important tools for amyotrophic lateral sclerosis (ALS) therapy development. Understanding their longitudinal trajectory in the untreated state is key to their use as potential markers of pharmacodynamic response.
Oleksandr Dergai, Joanne Wuu, Magdalena Koziczak‐Holbro, Andrea Malaspina, Volkan Granit, Jessica P. Hernandez, Anne Cooley, Ruchika Sachdev, Lili Yu, Michael Bidinosti, Ludivine Flotte, Mark Nash, Lori L. Jennings, James D. Berry, Lucie I. Bruijn, Sophie Brachat, Michael Benatar   +16 more
wiley   +1 more source

What One Can Learn From the Cloud Condensation Nuclei (CCN) Size Distributions as Monitored by the BEO Moussala?

, 2018
In this proceeding we report initial studies into the big data set acquired by the Cloud Condensation Nuclei (CCN) counter of the Basic Environmental Observatory (BEO) Moussala over the whole 2016 year at a frequency of 1 Hz.
Angelov, Ch., Arsov, T., Guerova, G., Kalapov, I., Kleshtanova, V., Tonchev, V.   +5 more
core   +1 more source

Surface‐Coated Inorganic Nanomaterials for Drug Delivery: Chemical Design, Biomedical Applications, and Mechanistic Insights

Advanced NanoBiomed Research, EarlyView.
This review explores how surface‐coated inorganic nanomaterials are chemically engineered for advanced drug delivery. It highlights design principles, coating strategies, and biomedical applications, emphasizing how surface chemistry governs biocompatibility, targeting, and controlled release.
Hossein Daneshgar, Sepideh Ahmadi, Nikzad Abbariki, Navid Rabiee, Sidi A. Bencherif   +4 more
wiley   +1 more source