Results 131 to 140 of about 956,443 (283)
Gamma oryzanol (GO), a phytosterol found most abundantly in rice bran oil as well as corn, barley, rye, vegetable oils and wheat bran. Thanks to its ability to slow down the development of melanin pigments, prevent the effects and spread of ultraviolet ...
Mac Thi Thanh Hoa +5 more
doaj +1 more source
Expression regulation of MAO isoforms in monocytic cells in response to Th2 cytokines [PDF]
Background: Th2-cytokines, such as interleukins-4 and –13 (IL-4, IL-13), have been identified as alternative stimuli of monocytes/macrophages. We have recently profiled the gene-expression pattern of IL-4-teated human peripheral monocytes and found that ...
Billett, E +4 more
core
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He +4 more
wiley +1 more source
High-performance liquid-chromatography of tetrapyrrole pigments [PDF]
Lempert, U. +3 more
core +1 more source
Glutathione (GSH) conjugates with dopamine (DA)-derived quinones to form reactive or non-reactive GSH-conjugates [PDF]
In this study we demonstrate for the first time that GSH could rapidly conjugate with dopamine (DA)-derived DA-o-quinones without enzymatic catalysis to form short-lived intermediate GSH-conjugates (2-S-GSH-DA-o-quinone and 5-S-GSH-DA-o-quinone).
Tit Meng Lim, Zhidong Zhou
core +1 more source
Over half of cancer patients undergo radiotherapy. Laser ablation enabled the synthesis of immiscible Au‐Fe‐B nanoparticles designed as degradable bimodal radiosensitizers for X‐ray radiotherapy (XRT), boron neutron capture therapy (BNCT), and bimodal imaging for X‐ray computed tomography (CT) and magnetic resonance imaging (MRI). These nanosensitizers
Michael Bissoli +15 more
wiley +1 more source
An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou +11 more
wiley +1 more source
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang +8 more
wiley +1 more source
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno +15 more
wiley +1 more source

