Results 51 to 60 of about 1,030,834 (343)

HPLC-MS characterisation of chelate modified somatropin [PDF]

, 2010
Somatropin is a recombinant human growth hormone, consisting of 191 amino acids. This protein is clinically used in children and adults with inadequate endogenous growth hormone to stimulate a normal bone and muscle growth.
De Spiegeleer, Bart, Pauwels, Ewald, Van De Wiele, Christophe, Van Dorpe, Sylvia, Vergote, Valentijn, Wynendaele, Evelien   +5 more
core  

Fast determination of biogenic amines in beverages by a core-shell particle column [PDF]

, 2015
A fast and reliable HPLC method for the determination of 11 biogenic amines in beverages has been performed. After pre-column derivatization with dansyl-chloride a Kinetex C18 core–shell particle column (100 mm × 4.6 mm, 2.6 μm particle size) has been ...
Giuliana Vinci, Marta Letizia Antonelli, Raffaella Preti, Roberta Bernacchia   +3 more
core   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Exploring the Brainpeps database [PDF]

, 2012
Since the discovery that peptides can cross the blood-brain barrier (BBB), doors have been opened to new therapeutics for CNS diseases and pain management.
Bracke, Nathalie, D'Hondt, Matthias, De Spiegeleer, Bart, Stalmans, Sofie, Wynendaele, Evelien   +4 more
core   +1 more source

Microwave Assisted Synthesis of Py-Im Polyamides [PDF]

, 2012
Microwave synthesis was utilized to rapidly build Py-Im polyamides in high yields and purity using Boc-protection chemistry on Kaiser oxime resin. A representative polyamide targeting the 5′-WGWWCW-3′ (W = A or T) subset of the consensus Androgen and ...
Bacsa B., Baird E. E., Bando T., Baptiste B., Chenoweth D. M., Chenoweth D. M., Chenoweth D. M., Choi J. S., Dale J. A., DeGrado W. F., Dervan P. B., Dervan P. B., Dose C., Edelson B. S., Farnham P. J., Harki D. A., Harris D., James W. Puckett, Joshua T. Green, Kappe C. O., Krutzik P. O., König B., Lai Y.-M., Murray J. K., Muzikar K. A., Nickols N. G., Olenyuk B. Z., Olivos H. J., Palasek S. A., Pelton J. G., Peter B. Dervan, Raskatov J. A., Sinyakov A. N., Su W., Turner J. M., Wade W. S., White S., Wurtz N. R., Xiao J. H.   +38 more
core   +2 more sources

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

Fatty Acid Composition, Tocopherol and Sterol Contents in Linseed (Linum usitatissimum L.) Varieties [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2017
The oil contents of linseeds were determined between 39.9% (Antares) and 43.3%  (Railinus). The oleic acid contents of seed oils varied between 0.8% (Maroc) and 24.8 (Railinus).
Bertrand Matthäus, Mehmet Musa Özcan
doaj  

Rhodiosin and herbacetin in Rhodiola rosea preparations: additional markers for quality control?

Pharmaceutical Biology, 2019
Context: Rhodiola rosea L. (Crassulaceae) is well-known to contain flavonoids such as the herbacetin derivative rhodiosin. However, flavonoids are not typically used in quality control. Objective: This study analyses two flavonoids of R.
Zoltán Péter Zomborszki, Norbert Kúsz, Dezső Csupor, Wieland Peschel   +3 more
doaj   +1 more source

STABILITY-INDICATING HPLC METHOD FOR ISOFLAVONES AGLYCONES ANALYSIS FROM TRIFOLIUM PRATENSE L. EXTRACT

Drug Analytical Research, 2020
The purpose of this study was to develop and validate a fast HPLC stability-indicating method for simultaneously quantifying the four main isoflavones in Trifolium pratense. Validation procedures followed the ICH requirements for complex matrices.
Simony Martiny, Mairique Waszczuk, Samuel Kaiser , Marina Cardoso Nemitz, Valquiria Linck Bassani   +4 more
doaj   +1 more source

Cyclophosphamide removal from water by nanofiltration and reverse osmosis membrane [PDF]

, 2009
The rejection of cyclophosphamide (CP) by nanofiltration (NF) and reverse osmosis (RO) membranes from ultrapure (Milli-Q) water and membrane bioreactor (MBR) effluent was investigated.
Albasi, Claire, Causserand, Christel, Dorandeu, Christophe, Faucet-Marquis, Virginie, Marion, Bénédicte, Pfohl-Leszkowicz, Annie, Wang, Li   +6 more
core   +1 more source