Results 61 to 70 of about 1,030,834 (343)

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Anticancer, Antioxidant, Antimicrobial Activities, and HPLC Analysis of Alcoholic Extracts of Parthenocissus quinquefolia L. Plant Collected from Çanakkale

Journal of Advanced Research in Natural and Applied Sciences
This study aimed to contribute to revealing the health effects of the Parthenocissus quinquefolia L. (PQ) plant by examining the biological activities of various extracts of the plant.
Sevil Kalın, Ersin Karabacak, Pınar Ilgın, Alper Önder, Özlem Maraba, Ferah Cömert Önder   +5 more
doaj   +1 more source

Quantification of rice bran oil in oil blends

Grasas y Aceites, 2012
Blends consisting of physically refined rice bran oil (PRBO): sunflower oil (SnF) and PRBO: safflower oil (SAF) in different proportions were analyzed for various physicochemical parameters.
R. Mishra, H. K. Sharma, G. Sengar
doaj   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

High-Performance Liquid Chromatography as a Novel Method for the Determination of α-Defensins in Synovial Fluid for Diagnosis of Orthopedic Infections

Diagnostics, 2020
The α-defensins (AD) present in synovial fluid have been regarded as constituting the most accurate periprosthetic joint infection (PJI) biomarker.
Pavel Melicherčík, Eva Klapková, Karel Kotaška, David Jahoda, Ivan Landor, Václav Čeřovský   +5 more
doaj   +1 more source

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Retention behavior of selected alkaloids in Reversed Phase micellar chromatographic systems

Current Issues in Pharmacy and Medical Sciences, 2015
In this work, the effects of sodium dodecyl sulfate (SDS) concentrations on retention, separation selectivity, peak shapes and systems efficiency were investigated. Herein, the retention data for 11 alkaloids were determined on an RP18 silica column with
Petruczynik Anna, Noster Grzegorz, Waksmundzka-Hajnos Monika   +2 more
doaj   +1 more source

Ceftaroline fosamil: development a rapid HPLC method indicating stability and bioassay for determination in pharmaceutical formulation, stability and cytotoxicity studies

Drug Analytical Research, 2021
The present study reports the development and validation of a microbiological assay. To assess this methodology, the method was developed and validated for the quantification of CEF by high performance liquid chromatography (HPLC).
Idamir José Mascarello Junior, Rafaela Martins Sponchiado, Leticia Malgarin Cordenonsi, Tércio Oppe Oppe, Elfrides Eva Scherman Shapoval   +4 more
doaj   +1 more source

A liquid chromatography tandem mass spectrometry method for simultaneous analysis of 46 atmospheric particulate-phase persistent organic pollutants and comparison with gas chromatography/mass spectrometry, [PDF]

, 2017
A novel multi-analyte method for the simultaneous determination of 46 compounds of environmental concern, most of them belonging to the category of persistent organic pollutants, was developed using high-performance liquid chromatography and the results ...
Buiarelli, Francesca, Di Filippo, Patrizia, Pomata, Donatella, Riccardi, Carmela, Bartocci, Martina   +4 more
core   +1 more source