Comparison of green enhanced fluidity reversed phase liquid chromatography with HPLC [PDF]
The growing interest in high throughput assays is the result of the increasing numbers and complexity of samples being produced by modern combinatorial synthetic procedures.
Admasu Engda, Engdawork+3 more
core
A Self-Replicating Peptide Nucleic Acid [PDF]
We report on a case of autocatalytic feedback in a template directed synthesis of a self-complementary hexa-PNA from two trimeric building blocks. The course of the reaction was monitored in the presence of increasing initial concentrations of product by means of RP-HPLC.
arxiv
Catch and release’ cascades: a resin-mediated three-component cascade approach to small molecules [PDF]
The application of a ‘catch and release’ approach to palladium-catalysed multi-component cascade reactions leads to diverse libraries of pharmacologically interesting small molecules in high yield and with excellent ...
Andrew Cook+23 more
core +1 more source
Exploring the Brainpeps database [PDF]
Since the discovery that peptides can cross the blood-brain barrier (BBB), doors have been opened to new therapeutics for CNS diseases and pain management.
Bracke, Nathalie+4 more
core +1 more source
Methods of the Analysis of Oxylipins in Biological Samples
Oxylipins are derivatives of polyunsaturated fatty acids and due to their important and diverse functions in the body, they have become a popular subject of studies.
Ivan Liakh+3 more
doaj +1 more source
Optical detection of Aflatoxins B in grained almonds using fluorescence spectroscopy and machine learning algorithms [PDF]
Aflatoxins are fungal metabolites extensively produced by many different fungal species that may contaminate a wide range of agricultural food products. They have been studied extensively because of being associated with various chronic and acute diseases especially immunosuppression and cancer and their presence in food is strictly monitored and ...
arxiv
Qualitative detection of oil adulteration with machine learning approaches [PDF]
The study focused on the machine learning analysis approaches to identify the adulteration of 9 kinds of edible oil qualitatively and answered the following three questions: Is the oil sample adulterant? How does it constitute? What is the main ingredient of the adulteration oil?
arxiv
Rhodiosin and herbacetin in Rhodiola rosea preparations: additional markers for quality control?
Context: Rhodiola rosea L. (Crassulaceae) is well-known to contain flavonoids such as the herbacetin derivative rhodiosin. However, flavonoids are not typically used in quality control. Objective: This study analyses two flavonoids of R.
Zoltán Péter Zomborszki+3 more
doaj +1 more source
Glutathione (GSH) conjugates with dopamine (DA)-derived quinones to form reactive or non-reactive GSH-conjugates [PDF]
In this study we demonstrate for the first time that GSH could rapidly conjugate with dopamine (DA)-derived DA-o-quinones without enzymatic catalysis to form short-lived intermediate GSH-conjugates (2-S-GSH-DA-o-quinone and 5-S-GSH-DA-o-quinone).
Tit Meng Lim, Zhidong Zhou
core +1 more source