Results 101 to 110 of about 110,023 (239)

Nationwide audit of cervical cancer screening reveals unsatisfactory triage strategies and trends over time in incidence among cytology negative women

International Journal of Cancer, EarlyView.
What's New? This population‐based cohort study aimed to demonstrate how annual audits of all aspects of the cervical cancer screening pathway can be performed using register national data with clinical validation to identify patterns of risk and inform program change.
Cecilia Kärrberg, Penelope Gray, Kristina Elfgren, Hanna Milerad, Bengt Andrae, Jiayao Lei, Pär Sparén, Joakim Dillner, Jiangrong Wang, K. Miriam Elfström   +9 more
wiley   +1 more source

Trends in the incidence of cancers of the breast and female genital tract in Harare, Zimbabwe 1990–2019

International Journal of Cancer, EarlyView.
What's New? Cancers of the breast and female genital tract represent more than half of all cancers in women in sub‐Saharan Africa. Here, the authors assessed incidence trends in a female population living in urban sub‐Saharan Africa based on the Zimbabwe National Cancer Registry in Harare over a 30‐year period.
Eric Chokunonga, Zvavahera Michael Chirenje, Margaret Borok, Rudo Makunike‐Mutasa, Ntokozo Ndlovu, Justice Mudavanhu, Biying Liu, D. Maxwell Parkin   +7 more
wiley   +1 more source

Yield of endocervical curettage in detecting cervical intraepithelial neoplasia grade 2 or higher during colposcopy: A prospective, cross‐sectional study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 105-111, April 2025.
Abstract Objective This study assessed the prevalence and factors associated with detecting cervical intraepithelial neoplasia grade 2 or higher (CIN2+) via endocervical curettage (ECC) during colposcopy. Methods Between December 2020 and September 2023, a prospective, cross‐sectional study involving women with abnormal cervical cancer screening ...
Nida Jareemit, Lalita Theerarojanapong, Natthawadee Laokulrath, Vuthinun Achariyapota, Khemanat Khemworapong, Sompop Kuljarasnont, Pornporm Ittiamornlert, Vitcha Poonyakanok, Perapong Inthasorn   +8 more
wiley   +1 more source

Loop electrosurgical excision procedure and perinatal outcomes post‐human papillomavirus cervical screening: A longitudinal cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study examines the associations between the loop electrosurgical excision procedure (LEEP) and the risk of adverse perinatal outcomes among women who have undergone primary human papillomavirus (HPV) screening. Methods In this longitudinal cohort study, women who received HPV screening and were followed up in a randomized trial ...
Quan Hong, Laurie W. Smith, Lily Proctor, Lovedeep Gondara, Saiful Alam, Darrel Cook, Eduardo L. Franco, Mel Krajden, Ruth Elwood Martin, Elisabeth McClymont, Joy Melnikow, Stuart Peacock, Gavin Stuart, Gina S. Ogilvie, Anna Gottschlich   +14 more
wiley   +1 more source

Microbiome‐urothelium crosstalk in bladder cancer: From dysbiosis to clinical translation

iMetaOmics, EarlyView.
This review elucidates the critical crosstalk between the urobiome and bladder cancer (BCa), mapping the landscape from ecological dysbiosis to clinical translation. We synthesize emerging evidence on microbial signatures that distinguish BCa patients, exploring key carcinogenic mechanisms including chronic inflammation, genotoxicity, and the gut ...
Haoxiang Xu, Zhibiao Li, Lin Yang, Jun Zheng, Weijia Li, Rulin Liao, Wenxue Huang, Boyuan Sun, Zhuohang Li, Cunzhen Ma, Xunguo Yang, Zongwei Wang, Jie Zhao, Bisheng Cheng, Peng Wu   +14 more
wiley   +1 more source

Microbial metabolites in tumor epigenetic regulation

iMeta, EarlyView.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang, Haoling Zhang, Yan Liao, Shuya Jiang, Haolong Zhang, Chenwei Huang, Zhijing Song, Rui Zhao, Ping Lu, Xiaohong Kang, Eryan Kong, Yalin Zhu, Wei Wang, Xuesong Liu, Yisheng Chen, Zhiwen Luo, Zhaoyu Li, Di Wang, Na Xing, Yadong Guo, Jingjing Zhang, Xiaojing Wang, Wenyi Wang, Mowaffaq Adam, Bakiah Shaharuddin, Muhamad Yusri Musa, Doblin Sandai, Chenglong Zhu, Aimin Jiang, Peng Luo, Zhijie Zhao, Zui Zou   +31 more
wiley   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Lymph‐based liquid biopsy: Current progress and future potential

Interdisciplinary Medicine, EarlyView.
Recent evidence under the revised Starling principle indicates that lymph‐based liquid biopsies may offer superior diagnostic performance over blood‐based counterparts in certain clinical scenarios, such as early‐stage solid tumor detection. Currently, various biomarkers within the lymphatic system show significant diagnostic potential for a range of ...
Dongdong Liu, Leheng Cheng, Xiaolin Hu, Sergio Bernardini, Hong Zhang, Ling Zhu, Yang Luo   +6 more
wiley   +1 more source

Stabilised Hyaluronic Acid Gel Rectal Spacers in MRI‐Guided Brachytherapy for Gynaecological Cancers: A Prospective Feasibility Study

Journal of Medical Radiation Sciences, EarlyView.
This prospective study investigated the feasibility of stabilised hyaluronic acid gel as a rectal spacer in gynaecological cancer brachytherapy. In twelve patients, the spacer was successfully inserted into the rectovaginal space without serious adverse events, had high visibility on MRI, increased the target‐to‐rectum distance compared with no spacer ...
Carminia Lapuz, Sylvia Hanna, Eddie Lau, Adeline Lim, Mark Tacey, Daryl Lim Joon, Claire Dempsey, Jenny Sim, Michael Chao   +8 more
wiley   +1 more source

Serological immunity against vaccine‐preventable diseases in children with inflammatory bowel disease at diagnosis

JPGN Reports, EarlyView.
Abstract Objectives Patients with inflammatory bowel disease (IBD) are at increased risk of vaccine‐preventable diseases. However, vaccination coverage in this population is often suboptimal. This retrospective study assessed the vaccination status and vaccine serology of children diagnosed with IBD in a high‐income country with broad vaccine access ...
Clara Noble, Renato Gualtieri, Klara Posfay‐Barbe, Nathalie Rock, Geraldine Blanchard‐Rohner   +4 more
wiley   +1 more source