Results 51 to 60 of about 291,345 (345)

Factores de Crescimento Hematopoiético

Revista Portuguesa de Pneumologia, 1995
SUMÁRIO: Os factores de crescimento hematopoiético (FCH) são glicoproteinas que regulam a proliferação e diferenciação das células sanguíneas.
Maria De Fátima Miguel Rodrigues, Margarida Cristóvão, Agostinho Costa, M.a José Melo   +3 more
doaj   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Effect of Preanalytical Processing of ThinPrep Specimens on Detection of High-Risk Human Papillomavirus by the Aptima HPV Assay [PDF]

, 2014
Two important preanalytical protocols performed on liquid-based cytological specimens, namely, automated cytology processing and glacial acetic acid (GAA) treatment, may occur prior to the arrival of specimens in a molecular diagnostics laboratory ...
Amrhein, Robert D., Bieganski, Theresa, Harkins, April L., Munson, Erik, Napierala, Maureen, Ross, Kevin C., Schroeder, Elizabeth R., Yauck, Connie   +7 more
core   +2 more sources

Pooled analysis of HPV infection in paired anal and cervical samples, by HIV status

Papillomavirus Research, 2018
Background: In light of HPV16's unique carcinogenicity in the anus, knowledge of anal HPV16 prevalence may be a useful surrogate for stratifying groups of women at differing anal cancer risk based on routinely available cervical cancer screening outcomes.
Gary Clifford, IARC HPV study group.
doaj   +1 more source

HPV Vaccines

Ağrı Tıp Fakültesi Dergisi
Human papillomavirus (HPV) is a double-stranded DNA virus and a source of infection that primarily affects the skin and mucous membranes. It can be transmitted through sexual contact and contaminated surfaces. There are over 200 genotypes of HPV, approximately 40 of which infect the anogenital region. High-risk HPV types, such as HPV-16 and HPV-18, can
Mehmet Yasin Yüksel, Funda Ekimci Deniz
openaire   +3 more sources

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

History of HPV in HPV-positive elderly women

European Journal of Obstetrics & Gynecology and Reproductive Biology: X
The aim of this study was to examine the natural course of HPV infection in women of 60 years and older who were HPV positive at inclusion, and any association between HPV positivity in historical samples and dysplasia outcome.Eighty-nine women aged 60-82 years, who tested positive for HPV between 2012 and 2016 were included.
Hermansson, Ruth S., Lillsunde-Larsson, Gabriella, Helenius, Gisela, Karlsson, Mats G., Kaliff, Malin, Olovsson, Matts, Lindström, Annika K   +6 more
openaire   +4 more sources

Dissolving Microneedle for Maintaining the Integrity of HPV Virus‐Like Particles Enabling Durable Sterile Protection Across Various Mucosal Tissues

Advanced Healthcare Materials, EarlyView.
A novel dissolving microneedle platform preserves HPV virus‐like particle (VLP) immunogenicity by maintaining structural integrity, crucial for eliciting potent immune responses. Buccal administration induces robust immune response, high neutralizing antibody titers, and durable sterile protection across oral and vaginal mucosal sites.
Hyemi Kim, Inhyuk Hwang, Juhee Seo, Chaiwon Kim, In‐Jeong Choi, Miran Kang, Min‐Seok Rha, Youngjae Hong, Jooyoung Kim, Seung‐Ki Baek, Jung‐Hwan Park, Hyung‐Ju Cho, Kihyuck Kwak   +12 more
wiley   +1 more source

Evidence for cross-protection but not type-replacement over the 11 years after human papillomavirus vaccine introduction [PDF]

, 2019
Examination of cross-protection and type replacement after human papillomavirus (HPV) vaccine introduction is essential to guide vaccination recommendations and policies.
Bernstein, David I., Brown, Darron, Covert, Courtney, Ding, Lili, Franco, Eduardo L., Kahn, Jessica A.   +5 more
core   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source