Results 91 to 100 of about 9,143 (202)

The Use of HPV16-E5, EGFR, and pEGFR as Prognostic Biomarkers for Oropharyngeal Cancer Patients

Frontiers in Oncology, 2018
Background: Anti-epidermal-growth-factor-receptor (EGFR) therapies in combination with radiotherapy are being studied on de-escalation clinical trials for HPV-related oropharyngeal cancer (OPC) patients.
Miren Taberna, Miren Taberna, Miren Taberna, Montserrat Torres, María Alejo, Marisa Mena, Marisa Mena, Sara Tous, Sara Tous, Sandra Marquez, Miquel A. Pavón, Xavier León, Xavier León, Jacinto García, Marta Guix, Marta Guix, Rafael Hijano, Teresa Bonfill, Antón Aguilà, Alicia Lozano, Ricard Mesía, Ricard Mesía, Ricard Mesía, Laia Alemany, Laia Alemany, Ignacio G. Bravo   +25 more
doaj   +1 more source

DNA‐Methylation for Risk‐Stratification of Women Without a Fully Visible Transformation Zone at Colposcopy: A Cross‐Sectional Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the performance of DNA methylation markers for the detection of cervical precancer among screening‐positive older women without a fully visible transformation zone at colposcopy (TZ3). Design Cross‐sectional study. Setting Colposcopy clinics, Central Denmark Region, 2019–2021.
Karen Omann Binderup, Joachim Boers, Line Winther Gustafson, Berit Andersen, Lone Kjeld Petersen, Pinar Bor, Joost Gribnau, Wim G. V. Quint, Henk Van Den Munckhof, Mette Tranberg, Anne Hammer   +10 more
wiley   +1 more source

Human papillomavirus genotype and prognosis of cervical cancer: Favorable survival of patients with HPV16-positive tumors

Papillomavirus Research, 2018
The prognostic impact of human papillomavirus (HPV) type on invasive cervical cancer (ICC) was analyzed for 137 women treated for ICC at a single institution between 1999 and 2007.
Mamiko Onuki, Koji Matsumoto, Yuri Tenjimbayashi, Nobutaka Tasaka, Azusa Akiyama, Manabu Sakurai, Takeo Minaguchi, Akinori Oki, Toyomi Satoh, Hiroyuki Yoshikawa   +9 more
doaj   +1 more source

Realgar, a traditional Chinese medicine, induces apoptosis of HPV16-positive cervical cells through a HPV16 E7-related pathway

, 2018
Wencheng Ding,1,* Teng Ji,1,* Wei Xiong,2 Tian Li,1 Demin Pu,1 Rong Liu1 1Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China ...
Ji T, Ding W, Li T, Liu R, Xiong W, Pu D
core  

Passive transfer of HPV16 L2 peptide antisera protects mice against vaginal challenge with HPV16.

, 2013
Mice were injected i.p. with 0.1 ml buffer or rabbit antiserum to KLH-coupled HPV16 L2 peptides encompassing residues 17–36, residues 32–51, residues 47–66, residues 65–81, 108–120, residues 373–392, or antiserum to HPV16 L1 VLP.
Kihyuck Kwak (278679), Vijayarangam Damotharan (278682), Sudha V. Chivukula (278683), Balasubramanyam Karanam (278680), Subhashini Jagu (278678), Warner K. Huh (278681), Richard B. S. Roden (278684)   +6 more
core   +1 more source

Efficacy and Safety of Anal High‐Grade Squamous Intraepithelial Lesion Treatment Modalities: A Systematic Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background There is compelling evidence that treating high‐grade squamous intraepithelial lesions (HSIL), the anal squamous cell cancer (ASCC) precursor, reduces the risk of developing ASCC. Using high‐resolution anoscopy (HRA), surgical excision, ablative and topical therapies are widely used to treat HSIL.
Matthew Joseph Marino, Sophie Jones, Nicholas Reid Caldwell, Catherine Cartwright, Benedict Blacket, Richard Clive Turner   +5 more
wiley   +1 more source

Introducing self‐sampling for cervical cancer screening: A regional implementation study in Pirkanmaa, Finland

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this pilot study, HPV self‐sampling reached a 1.9% uptake among screening non‐attenders. Participants found the method acceptable, although overall screening coverage did not increase during the first implementation year. Abstract Introduction HPV primary testing is the preferred method for cervical cancer screening worldwide and enables vaginal ...
Saara Kyllönen, Satu Saloranta, Saara Kares, Anu Mustila, Karolina Louvanto   +4 more
wiley   +1 more source

HPV16 E6WT, E6I128T and E6Δ146–151 mutant genomes but not HPV16 E6SAT are maintained extrachromosomally in clones.

, 2013
(A) HPV16 WT replicated extrachromosomally in a clone as indicated by the presence of open circular (OC), linear (LN) and supercoiled (SC) HPV16 DNA after XhoI/DpnI digestion of total genomic DNA. Passage 6 DNA is shown.
Paul F. Lambert (266676), Laurel D. Lorenz (476549), Jessenia Rivera Cardona (476550)   +2 more
core   +1 more source

HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann, Ulrike Wieland, Steffi Silling, Frank Oellig, David Chromy, Julia Hyun, Thilo Gambichler, Alexander Kreuter   +7 more
wiley   +1 more source

A novel fluorescence immunoassay for the quantitative detection of HPV16 L1 antibodies in human serum samples using ZnCdSe/ZnS quantum dot-labeled antibodies

Microbiology Spectrum
Human papillomavirus type 16 (HPV16) is a high-risk virus linked to cervical cancer, primarily through its oncogenic proteins E6 and E7. The HPV16-L1 protein, the major capsid component, plays a key role in capsid formation and immune response ...
Aiping Wang, Cheng Xin, Zhuting Chen, Jingming Zhou, Yumei Chen, Yankai Liu, Hongliang Liu, Chao Liang, Xifang Zhu, Yanhua Qi, Gaiping Zhang   +10 more
doaj   +1 more source