Results 161 to 170 of about 63,318 (271)

Ruthenium‐Catalyzed Nitrile‐Acrylate Reductive Coupling by 2‐Propanol: Synthesis of Enantioenriched β‐Amino Esters

open access: yesAngewandte Chemie, EarlyView.
The first nitrile reductive couplings beyond stoichiometric metals or metalloids are described. Using a ruthenium catalyst derived from RuHCl(CO)(PPh3)3 and Cy‐BIPHEP, 2‐propanol‐mediated reductive coupling of phenyl acrylate with aromatic or aliphatic nitriles delivers α,β‐unsaturated β‐amino esters.
Sebastian Höthker   +3 more
wiley   +2 more sources

Impact of strategy, HRM Strength and HRM bundles on innovation performance and organizational performance [PDF]

open access: yes
This study uses structural equation modeling to test a model of the impact of human resource management bundles on perceived organizational performance and innovation performance, on a large sample of companies.
Cunha, Miguel Pina e   +1 more
core  

Adenylation Domain Engineering Enables Biosynthesis of an Improved Polymyxin Antibiotic

open access: yesAngewandte Chemie, EarlyView.
To enable incorporation of l‐2‐aminodecanoic acid into polymyxin by fermentation, a single Trp‐to‐Ala substitution is rationally introduced into the adenylation‐domain residue of its nonribosomal peptide synthetase (NRPS) and efficiently switches substrate selectivity. The engineered strain produces biologically active Ada‐polymyxin, demonstrating that
Maximilian Müll   +7 more
wiley   +2 more sources

Zirkuläre, Photogeschützte mRNA für Lichtinduzierte Aktivierung der Translation zu späten Zeitpunkten

open access: yesAngewandte Chemie, EarlyView.
Eine klickbare, photogeschützte 5′‐Kappe (CyCliCap) zur Herstellung von zyklischer, Click‐Cap enthaltender mRNA (Cyclic Click Cap‐mRNA), die bis zur Bestrahlung beachtlich stabil und translational stumm ist, ermöglicht die Aktivierung der Translation in Zellen zu späten Zeitpunkten mittels Lichts. ZUSAMMENFASSUNG mRNA ist eine neue Impfstofftechnologie
Bayram Terzi   +6 more
wiley   +1 more source

SOD1:c.118G>A mutation in the Cimarrón Uruguayo dog: prevalence, drift dynamics, and structural effects. [PDF]

open access: yesBraz J Vet Med
Artigas R   +6 more
europepmc   +1 more source

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