Results 51 to 60 of about 48,111 (219)

Ultrasound‐Triggered piRNA Delivery Using Biomimetic Phase‐Changeable Nanoparticles for Theranostics of Myocardial Infarction

Advanced Science, EarlyView.
A biomimetic ultrasound‐responsive piRNA delivery nanoparticle platform (piR‐NPs) enables targeted delivery and ultrasound (US)‐triggered release of piR‐1873 in infarcted myocardium. The released piR‐1873 suppresses Usp2‐mediated RIP1/RIP3/MLKL necroptosis, reduces myocardial injury and fibrosis, and promotes cardiac functional recovery, providing a ...
Yajun Zhang, Hongzhao Qi, Yanyan Yang, Feng Wang, Tiantian Han, Yanbei Lei, Xiaolu Li, Zhibin Wang, Hua Qu, Tao Yu, Pin Sun   +10 more
wiley   +1 more source

Correlation of high-sensitivity C-reactive protein with blood sugar level in patients with Type 2 diabetes

National Journal of Physiology, Pharmacy and Pharmacology, 2018
Background: The prevalence of diabetes is rapidly rising all over the globe at an alarming rate. Complications of diabetes include microvascular and macrovascular complications.
Leya Elizabeth Babu, Anuradha Joshi
doaj   +1 more source

Impact of Dual Interleukin‐17A and Interleukin‐17F Inhibition With Bimekizumab on Inflammatory and Structural Lesions in Axial Spondyloarthritis: Magnetic Resonance Imaging and Radiographic Outcomes From Two Phase 3 Studies and Their Open‐Label Extension

Arthritis &Rheumatology, EarlyView.
Graphical Abstract Objective To evaluate the impact of bimekizumab, a dual interleukin (IL)‐17A and IL‐17F inhibitor, on sacroiliac joints (SIJ) and spine inflammation/structural damage in axSpA using magnetic resonance imaging (MRI) scans/radiographs from the phase 3 studies BE MOBILE 1 (non‐radiographic axSpA [nr‐axSpA]) and 2 (radiographic axSpA [r ...
Walter P. Maksymowych, Sofia Ramiro, Denis Poddubnyy, Xenofon Baraliakos, Robert G. W. Lambert, Ute Massow, Tom Vaux, Chetan Prajapati, Alexander Marten, Natasha de Peyrecave, Mikkel Østergaard   +10 more
wiley   +1 more source

Outcomes of Tapering Biologic and Targeted Synthetic Disease‐Modifying Antirheumatic Drugs in Rheumatoid Arthritis: A Multicenter Randomized Noninferiority Trial

Arthritis &Rheumatology, EarlyView.
Objective Evidence supporting tapering of biologic or targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) in patients with rheumatoid arthritis (RA) with sustained low disease activity (LDA) remains limited. We evaluated the efficacy and safety of a structured b/tsDMARD‐tapering strategy in patients with RA who had achieved sustained ...
Dong‐Jin Park, Sung‐Eun Choi, Ji‐Hyoun Kang, Jung‐Yoon Choe, Hye‐Soon Lee, So‐Young Bang, Yun‐Hong Cheon, Sang‐Il Lee, Mingyo Kim, Yoon‐Kyoung Sung, Soo‐Kyung Cho, Jae Hyun Jung, Sung Hae Chang, Sung Won Lee, Yeon‐Ah Lee, Seung‐Geun Lee, Hyun‐Sook Kim, Seung‐Ki Kwok, Seung‐Cheol Shim, Shin‐Seok Lee   +19 more
wiley   +1 more source

Experimental Investigation on the Effect of Dry and Wet Activation Processes on the Morphological Properties of Activated Carbon Derived From Sugarcane Bagasse

Carbon Innovation, EarlyView.
Synthesis and characterization of sugarcane bagasse‐derived activated carbon via KOH‐assisted dry and wet activation. ABSTRACT This study explores the impact of activation processes on the morphological properties of activated carbon. Carbon is initially produced through vacuum pyrolysis at three temperatures (500°C, 600°C, and 700°C), with a heating ...
Sachin Channappa Hallad, N. L. Panwar, Kavankumar Venkatareddy, J. K. Maherchandani, Trilok Gupta, S. S. Meena   +5 more
wiley   +1 more source

Troponin T but not C reactive protein is associated with future surgery for aortic stenosis: a population-based nested case-referent study

Open Heart, 2020
Aims High-sensitivity troponin T (hs-TnT) and high-sensitivity C reactive protein (hs-CRP) may convey prognostic information in patients with aortic stenosis (AS).
Bengt Johansson, Stefan Söderberg, Anders Holmgren, Johan Ljungberg, Johan Hultdin, Ingvar A Bergdahl, Ulf Näslund   +6 more
doaj   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

Low High‐Sensitivity C‐Reactive Protein Level in Korean Patients With Chronic Kidney Disease and Its Predictive Significance for Cardiovascular Events, Mortality, and Adverse Kidney Outcomes: Results From KNOW‐CKD

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Inflammation levels are lower in East Asians than in Western people. We studied the association between high‐sensitivity hs‐CRP (C‐reactive protein) and adverse outcomes in Korean patients with chronic kidney disease.
Changhyun Lee, Keun Hyung Park, Young Su Joo, Ki Heon Nam, Tae‐Ik Chang, Ea Wha Kang, Joongyub Lee, Yun Kyu Oh, Ji Yong Jung, Curie Ahn, Kyu‐Beck Lee, Jung Tak Park, Tae‐Hyun Yoo, Shin‐Wook Kang, Seung Hyeok Han   +14 more
doaj   +1 more source

Incidence and impact of respiratory tract infections on outcomes in patients with status epilepticus: A 20‐year longitudinal observation

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to identify the incidence of respiratory tract infections (RTIs) in a large cohort of adult patients with status epilepticus (SE) and to characterize their associations with clinical features and outcome determinants.
Sebastian Berger, Sira M. Baumann, Urs Fisch, Lisa Hert, Pascale Grzonka, Sabina Hunziker, Stephan Rüegg, Sarah Tschudin‐Sutter, Raoul Sutter   +8 more
wiley   +1 more source

Comparison of C-reactive protein and high-sensitivity C-reactive protein levels in patients on hemodialysis

Saudi Journal of Kidney Diseases and Transplantation, 2012
Chronic inflammation is highly prevalent in patients on hemodialysis (HD), as evidenced by increased levels of C-reactive protein (CRP). We compared CRP to high-sensitivity C-reactive protein (hs-CRP) to determine whether it has any clinical implications
Imed Helal, Lilia Zerelli, Madiha Krid, Fethi ElYounsi, Hedi Ben Maiz, Bechir Zouari, Jaouida Adelmoula, Adel Kheder   +7 more
doaj   +1 more source