Results 61 to 70 of about 63,749 (300)

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Impact of Abdominoperineal Resection on Postoperative Male Sexual Function After Minimally Invasive Rectal Cancer Surgery: A Subgroup Analysis From the LANDMARC Study

Annals of Gastroenterological Surgery, EarlyView.
Abdominoperineal resection (APR) after minimally invasive rectal cancer surgery was associated with significantly higher rates of erectile and early ejaculatory dysfunction compared with anal‐sparing surgery. Although ejaculatory function showed partial recovery over time, erectile dysfunction persisted up to 12 months postoperatively.
Taiki Kajiwara, Shinobu Ohnuma, Michiaki Unno, Masakatsu Numata, Tomohiro Yamaguchi, Koya Hida, Tomonori Akagi, Suguru Hasegawa, Akio Shiomi, Ryo Inada, Manabu Shiozawa, Keisuke Kazama, Masanori Hotchi, Masahiko Watanabe, Takeshi Naitoh   +14 more
wiley   +1 more source

The relationship between high-sensitivity C-reactive protein and gallstones: a cross-sectional analysis

Frontiers in Medicine
Background and objectiveHigh-sensitivity C-reactive protein (hs-CRP), a classical indicator of inflammation, holds significant clinical value in various diseases. The relationship between hs-CRP and gallstones, however, remains poorly studied at present.
Zhimeng Jiang, Zhimeng Jiang, Huixin Jiang, Xingyu Zhu, Xingyu Zhu, Donglin Zhao, Donglin Zhao, Feifei Su   +7 more
doaj   +1 more source

PETANDA PERADANGAN hs CRP DENGAN HIPERTENSI

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2018
The major pathophysiologic mechanisms of hypertension include the activation of sympathetic nervous system and rennin–angiotensin–aldosterone system. Endothelial dysfunction, increased vascular reactivity, and vascular remodeling may cause that matter,rather than its consequences, of blood pressure elevation; increased vascular stiffness, which ...
Suswanto ., Siti Muchayat P
openaire   +2 more sources

Hyperhomocysteinemia, Insulin Resistance and High HS- CRP Levels in Prehypertension

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2014
Pre-hypertension refers to blood pressure in the range of 120 to 139 mm of Hg / 80 to 89 mm of Hg and its prevalence is increasing in India. Previous studies have documented the increase in homocysteine, C-reactive protein and insulin resistance and their role in the development of hypertension.
Prashanth Talikoti, Zachariah Bobby, Abdoul Hamide   +2 more
openaire   +3 more sources

Relationship Between Protein Types and hs-CRP on eGFR

UF Journal of Undergraduate Research, 2023
Few studies have measured the relationship between protein types and inflammation on kidney function among US adults. The objective was to identify the relationship between protein types (animal, dairy, plant, seafood) and high-sensitivity C-reactive protein on estimated glomerular filtration rate (eGFR).
Anthony Dispensa, Jeanette Andrade
openaire   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

Independent Prognostic Value of High-sensitivity C-reactive Protein in Patients with Coronary Artery Ectasia

Chinese Medical Journal, 2016
Background: Despite its severity, coronary artery ectasia (CAE) is still poorly understood. High-sensitivity C-reactive protein (hs-CRP) has been recognized as a prognostic factor in some cardiovascular diseases but not assessed in CAE.
Yintang Wang, Yang Wang, Shijie You, Hongjian Wang, Dong Yin, Kefei Dou, Weihua Song   +6 more
doaj   +1 more source

Cigarette smoking worsens systemic inflammation in persons with metabolic syndrome [PDF]

, 2014
Background Emerging data suggests that the combination of smoking and metabolic syndrome (MetS) markedly increases cardiovascular disease risk well beyond that of either condition.
Agatston, Arthur, Ali, Shozab S., Aneni, Ehimen C., Blaha, Michael J., Blumenthal, Roger S., Carvalho, Jose A., Conceicao, Raquel D., Feldman, Theodore, Jamal, Omar, McEvoy, John W., Nasir, Khurram, Parris, Don, Santos, Raul D., Shaharyar, Sameer, Veledar, Emir   +14 more
core   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source