Results 41 to 50 of about 23,840 (199)

Students engagement using polls in virtual sessions of physiology, pathology, and pharmacology at King Saud bin Abdulaziz University for Health Sciences during COVID-19 pandemic: a cross-sectional study

BMC Medical Education, 2023
Background Active involvement of students in class using technology is associated with effective learning and understanding. This work intended to analyze the impact of interactive teaching on medical students’ engagement, learning, performance ...
Mona Abubakr Bawazeer, Saima Aamir, Fatmah Othman, Reem Alkahtani   +3 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Spectrum of Haemoglobinopathies: A Hospital Based Study in Uttarakhand [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Haemoglobinopathy is a worldwide inherited problem as recognized by WHO and care of affected patients incurs heavy expense on the limited resources of developing countries.
Shivani Nayar, Seema Acharya, Rajiv Acharya, Sanjeev Kishore, Brijesh Thakur   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Conscientious objection in pharmacist codes of ethics: An international comparison through document analysis

Exploratory Research in Clinical and Social Pharmacy
Background: Conscientious objection (CO) in pharmacy refers to the refusal to provide certain services based on moral or religious beliefs. Person-centred care helps to carve a way forward in balancing the duality of private conscience and public role ...
L.S. Wong, S.L. Scahill, E. Barton, X.Y. Lim, J. Hikaka, J. Boey, D.J. Exeter, M. Hudson, A. Nu'u, Sanyogita (Sanya) Ram   +9 more
doaj   +1 more source

An Efficient Application of the MOEA/D Algorithm for Designing Noise Abatement Departure Trajectories

Aerospace, 2017
In an effort to allow to increase the number of aircraft and airport operations while mitigating their negative impacts (e.g., noise and pollutant emission) on near-airport communities, the optimal design of new departure routes with less noise and fuel ...
Vinh Ho-Huu, Sander Hartjes, Hendrikus G. Visser, Richard Curran   +3 more
doaj   +1 more source

What is the volume, diversity and nature of recent, robust evidence for the use of peer support in health and social care? An evidence and gap map

Campbell Systematic Reviews, 2022
Background Peer support interventions involve people drawing on shared personal experience to help one another improve their physical or mental health, or reduce social isolation.
Anna Price, Siân deBell, Naomi Shaw, Alison Bethel, Rob Anderson, Jo Thompson Coon   +5 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Experimental study of regenerative wind farms featuring enhanced vertical energy entrainment [PDF]

Wind Energy Science
This study presents the experimental validation of regenerative wind farms (RGWFs), a novel wind farm concept designed to enhance overall wind farm performance.
Y. Li, M. Fijen, B. Dsouza, W. Yu, A. Sciacchitano, C. Ferreira   +5 more
doaj   +1 more source