Results 41 to 50 of about 500,134 (199)
Exploratory Research in Clinical and Social PharmacyBackground: Conscientious objection (CO) in pharmacy refers to the refusal to provide certain services based on moral or religious beliefs. Person-centred care helps to carve a way forward in balancing the duality of private conscience and public role ...
L.S. Wong +9 more
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Campbell Systematic Reviews, 2022 Background Peer support interventions involve people drawing on shared personal experience to help one another improve their physical or mental health, or reduce social isolation.
Anna Price +5 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Experimental study of regenerative wind farms featuring enhanced vertical energy entrainment [PDF]
Wind Energy ScienceThis study presents the experimental validation of regenerative wind farms (RGWFs), a novel wind farm concept designed to enhance overall wind farm performance.
Y. Li +5 more
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Initial engagement and axial force model for self-tapping bone screws
Current Directions in Biomedical Engineering, 2022 Correctly torquing bone screws is important for implant fixation longevity and strength. A model-based smart screwdriver has been proposed to regulate torque, however current models ignore axial force and the initial engagement of the screw.
Wilkie Jack, Rauter Georg, Möller Knut
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Materials Research Express, 2019 Polymer-piezoceramic composites have drawn a lot of attention for sensor and energy harvesting applications. Poling such materials can be difficult due to the electric field getting mostly distributed over the low dielectric constant matrix.
Vincent L Stuber +3 more
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Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source