Background Heat-stable antifungal factor (HSAF) is a newly identified broad-spectrum antifungal antibiotic from the biocontrol agent Lysobacter enzymogenes and is regarded as a potential biological pesticide, due to its novel mode of action. However, the
Bao Tang +5 more
doaj +1 more source
Subsurface structure identification at the blind prediction site of ESG6 based on the earthquake-to-microtremor ratio method and diffuse field concept for earthquakes [PDF]
We participated in the blind prediction exercise organized by the committee of the blind prediction experiment during the 6th International Symposium on Effects of Surface Geology on Seismic Motion (CBP-ESG6).
Ito, Eri +3 more
core +1 more source
Structure and Biosynthesis of Heat-Stable Antifungal Factor (HSAF), a Broad-Spectrum Antimycotic with a Novel Mode of Action [PDF]
ABSTRACT A screen for antifungal compounds from Lysobacter enzymogenes strain C3, a bacterial biological control agent of fungal diseases, has previously led to the isolation of heat-stable antifungal factor (HSAF). HSAF exhibits inhibitory activities against a wide range of
Yu, Fengan +8 more
openaire +2 more sources
経験的手法に基づく地盤の線形および非線形挙動を考慮した地震時地盤増幅特性に関する総合的研究 [PDF]
京都大学新制・課程博士博士(工学)甲第24603号工博第5109号新制||工||1977(附属図書館)京都大学大学院工学研究科建築学専攻(主査)教授 松島 信一, 教授 竹脇 出, 教授 池田 芳樹学位規則第4条第1項該当Doctor of Philosophy (Engineering)Kyoto ...
Wang, Ziqian
core +1 more source
Transcriptomics Analysis of the Chinese Pear Pathotype of Alternaria alternata Gives Insights into Novel Mechanisms of HSAF Antifungal Activities [PDF]
Alternaria alternata (Fries) Keissler is a lethal pear pathogen that causes leaf black spot disease of pear in Southern China. Heat-stable activity factor (HSAF) is a polycyclic tetramate macrolactam (PTM) produced by Lysobacter enzymogenes and many other microbes with a broad-spectrum antifungal activity against many filamentous fungi.
Feng He +9 more
openaire +2 more sources
Use of the tetrazolium salt MTT to measure cell viability effects of the bacterial antagonist Lysobacter enzymogenes on the filamentous fungus Cryphonectria parasitica [PDF]
Despite substantial interest investigating bacterial mechanisms of fungal growth inhibition, there are few methods available that quantify fungal cell death during direct interactions with bacteria.
Bradley I. Hillman +3 more
core +1 more source
Identification of a small molecule signaling factor that regulates the biosynthesis of the antifungal polycyclic tetramate macrolactam HSAF in Lysobacter enzymogenes [PDF]
Lysobacter species are emerging as new sources of antibiotics. The regulation of these antibiotics is not well understood. Here, we identified a small molecule metabolite (LeDSF3) that regulates the biosynthesis of the antifungal antibiotic heat-stable antifungal factor (HSAF), a polycyclic tetramate macrolactam with a structure and mode of action ...
Yong, Han +9 more
openaire +2 more sources
Summary YajQ, a binding protein of the universal bacterial second messenger cyclic di‐GMP (c‐di‐GMP), affects virulence in several bacterial pathogens, including Xanthomonas campestris. In this bacterium, YajQ interacts with the transcription factor LysR.
Sen Han +6 more
wiley +1 more source
Human Albumin Fragments Nanoparticles as PTX Carrier for Improved Anti-cancer Efficacy
For enhanced anti-cancer performance, human serum albumin fragments (HSAFs) nanoparticles (NPs) were developed as paclitaxel (PTX) carrier in this paper.
Liang Ge +10 more
doaj +1 more source
Heat-Stable Antifungal Factor (HSAF) Biosynthesis in Lysobacter enzymogenes Is Controlled by the Interplay of Two Transcription Factors and a Diffusible Molecule [PDF]
ABSTRACT Lysobacter enzymogenes is a Gram-negative, environmentally ubiquitous bacterium that produces a secondary metabolite, called heat-stable antifungal factor (HSAF), as an antifungal factor against plant and animal fungal pathogens.
Zhenhe, Su +4 more
openaire +2 more sources

