Results 11 to 20 of about 18,501 (187)

Nonavalent HPV vaccine to prevent recurrent anal or vulvar high-grade squamous intraepithelial lesions (VIVA trial): A randomized, double-blind, placebo-controlled trial. [PDF]

Int J Cancer
What's new? Anal and vulvar high‐grade squamous intraepithelial lesions (HSILs) frequently recur following treatment. Additional genital and anal procedures, however, can be distressing for patients and are potentially disfiguring. This trial assessed whether the 9‐valent human papillomavirus (9vHPV) vaccine reduces HSIL recurrence risk or HPV ...
Stankiewicz Karita HC, Magaret AS, Doody DR, Schouten JT, Mao C, Huh WK, Grieco VS, Seymour MA, Varon D, Shrader KH, Xi LF, Galloway DA, Wald A, Madeleine MM.   +13 more
europepmc   +2 more sources

Performance of P16INK4a immunocytochemical stain in facilitating cytology interpretation of HSIL for HPV-positive women aged 50 and above

Frontiers in Oncology
BackgroundFew articles have focused on the cytological misinterpretation of high-grade squamous intraepithelial lesion (HSIL). Due to estrogen deficiency, cervical epithelial cells in postmenopausal women tend to show atrophic change that looks like HSIL
Hui Du, Fangbin Song, Xinfeng Qu
exaly   +3 more sources

Antitumor immune cycle proteins and HPV status in patients with HSIL and cervical cancer [PDF]

Гинекология, 2023
Background. Cervical cancer (CC) is a common malignant tumor among women worldwide. The anti-tumor immune cycle (AIC) is a necessary molecular mechanism that prevents the occurrence and progression of a tumor.
Elena V. Kayukova, Tatiana E. Belokrinitskaya, Svetlana V. Romanyuk   +2 more
doaj   +1 more source

FEN1 plays a key role in the transition from HSIL to CSCC

Scientific Reports
Cervical high-grade squamous intraepithelial lesion (HSIL) is a well-recognized precursor to cervical squamous cell carcinoma (CSCC). This study aims to explore molecular mechanisms underlying this transition.
Fengxian Zhang, Xiaomei Chen, Chenyang Chu, Meilin Chen, Ying Yang, Yanting You, Jie Zhou, Pingping Jiang, Ni Song, Yunhong Yu, Yanyan Liu   +10 more
doaj   +3 more sources

Effect of combined therapy polyhexamethylene biguanide and Coriolus-MRL on human papilloma virus (HPV) cervical and vulvar-related lesions [PDF]

International Journal of Medical Device and Adjuvant Treatments, 2020
OBJECTIVE: Human papillomavirus (HPV) persistent infections of genital tract are strongly related to the development of genital warts and cellular transformation.
D. Gincheva, V. Gincheva, E. Konova
doaj   +1 more source

The incidence of HPV infection of high carcinogenic risk in women of the Kemerovo region [PDF]

Гинекология, 2023
Aim. Toassess the prevalence of various types of human papillomavirus (HPV) of high carcinogenic risk (HCR) and the rate of abnormal findings of cytological examination in HPV-positive and HPV-negative women of the Kemerovo region.
Natalia V. Artymuk, Anastasia V. Breus, Dmitrii A. Artymuk   +2 more
doaj   +1 more source

Особенности мазков Папаниколау у женщин репродуктивного периода жизни с папилломавирусом 16, 18

Український журнал Перинатологія і педіатрія, 2021
Согласно современным данным, заболевания шейки матки возникают неслучайно. Предраковые поражения варьируются от человека к человеку и через определенный период становятся инвазивными.
Shafag Eldar Aliyeva
doaj   +1 more source

Comparison of the results of clinical and morphological methods of research in HPV-associated diseases of the cervix (retrospective study)

Гинекология, 2021
Aim. To conduct a retrospective analysis and evaluate the morphological methods for HPV-related intraepithelial lesions detection in women of reproductive age. Materials and methods.
Djamilya I. Attoeva, Alexandra V. Asaturova, Vera N. Prilepskaya, Nataliia L. Starodubtseva, Polina L. Sheshko, Ada T. Uruymagova   +5 more
doaj   +1 more source

P16INK4a/ki67 immunocytochemistry in improving the predictive value for high grade cervical intraepithelial (≥CIN2) neoplasia in pap smear

Journal of Cytology, 2021
Introduction: Cervical cytology has limited sensitivity to detect cervical pre-cancerous lesions. High-risk human papillomavirus (hr-HPV) DNA testing has high sensitivity but its specificity is limited.
G Vinoth Kumar, Anne Jennifer Prabhu, Ajit Sebastian, Raghavendran, Priya Abraham, Abraham Peedicayil   +5 more
doaj   +1 more source

Study of histopathology reports of loop electrosurgical excision procedure of cervical transformation zone and their correlation with preprocedural cervical biopsy and/or cytology: An audit

Indian Journal of Pathology and Microbiology, 2022
Introduction: Loop electrosurgical procedure of the transformation zone of the cervix (LEEP) is the preferred method for many investigators for early detection and treatment of high grade intraepithelial neoplasia(HGCIN).
Kedar K Deodhar, Devmalya Banerjee, Bharat Rekhi, Santosh Menon, Saleem Pathuthara   +4 more
doaj   +1 more source