Results 181 to 190 of about 40,103 (213)

Hsp60 in Inflammatory Disorders

2019
Heat shock proteins (HSP) including HSP60 are immunogenic proteins shared by particular microbial agents and mammals. HSP60 has been implicated in multiple inflammatory disorders and autoimmune diseases mostly through its interactions with the immune system.
Antonella Marino Gammazza, Giovanni Tomasello, Angelo Leone, Abdo Jurjus   +3 more
openaire   +1 more source

Biology of Extracellular HSP60

2019
The exposure of cells or organisms to high temperature leads to the release of alert molecules such as Heat Shock Protein: the HSP. This protein family has been initially described in Drosophila. The cellular response to a heat shock involving HSP is conserved across species, from bacteria to humans and including plants.
Brice Nativel, Cynthia Planesse, Philippe Gasque, Christine Robert Da Silva, Olivier Meihac, Wildriss Viranaïcken   +5 more
openaire   +1 more source

THE UNIVERSALLY CONSERVED GroE (Hsp60) CHAPERONINS

Annual Review of Microbiology, 1991
INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . .. . . .. . . .. . . . . ... ...... . . . . . . . . . . . . . . . . ... . . . . . . . . . . 301 THE groE OPERON . . . . . . . . . . . .... . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
J, Zeilstra-Ryalls, O, Fayet, C, Georgopoulos   +2 more
openaire   +2 more sources

Sequence homologies between hsp60 and autoantigens

Immunology Today, 1993
The human heat shock protein (hsp) 60 shares sequence homology with a wide range of autoantigens including those of insulin dependent diabetes mellitus, Hashimoto's thyroiditis, glomerulonephritis, scleroderma, pemphigoid, rheumatoid arthritis, multiple sclerosis, chronic active hepatitis, primary biliary cirrhosis and Addison's disease.
D B, Jones, A F, Coulson, G W, Duff
openaire   +2 more sources

?????????????????? ?????????????????????????????? ???????????????? GroEL ?? ?????? ???????????????????????????????? ??????????-???????????????????????? ?? Hsp60

2019
The method of obtaining and purification of recombinant chaperon GroEL (prokaryotic homolog of eukaryotic chaperon Hsp60) including the protein expression in E. coli cells, precipitation with saturated ammonium sulphate from a producent lysate, gel-filtration on Sephacryl-300 column and ion-exchange chromatography on MonoQ HR 5/5 column, is described ...
openaire   +2 more sources

Hsp60 Inhibitors and Modulators

2019
In this chapter, we focus on the 60 KDa Heat Shock Protein (Hsp60) and discuss some of its biological, molecular and pathological features. The structural and mechanistic aspect of the Hsp60 folding cycle will be also presented. We further illustrate how Hsp60 may be involved in many diseases and therefore considered as an effective therapeutic or ...
Palumbo Piccionello, Antonio, Marzullo, Paola, Buscemi, Silvestre, Pace, Andrea   +3 more
openaire   +2 more sources

474: HSP60 and anti-HSP60 antibody are associated with intrapartum infection in preeclamptic mothers

American Journal of Obstetrics and Gynecology, 2007
INFECTION IN PREECLAMPTIC MOTHERS MARK SANTILLAN, DONNA SANTILLAN, JOHN GIANOPOULOS, RUBIN MESTRIL, MEGAN KOH, University of Iowa, Iowa City, Iowa, Loyola University Medical Center, Maywood, Illinois OBJECTIVE: The role of heat shock protein 60 (HSP60) in pregnancy is unclear.
Mark Santillan, Donna Santillan, John Gianopoulos, Rubin Mestril, Megan Koh   +4 more
openaire   +1 more source

RT-PCR Quantitation of HSP60 mRNA Expression

2003
Heat shock protein 60 (HSP60, HSPD1) is a "chaperonin" that facilitates folding of nascent proteins into proper conformations (1). It is thought to play a critical role in the assembly, folding, and transport of proteins in the mitochondria. HSP60 also interacts with nascent cellular proteins to prevent their denaturation under heat stress (2).
R P, Perez, L, Pendyala, Z, Elakawi, M, Abu-Hadid   +3 more
openaire   +2 more sources

Hsp60 and Hsp10 in Ageing

2009
HSP and molecular chaperones, both referred to in this chapter as chaperones, are key players in development and senescence. With regard to senescence, several issues are critical: the role of normal chaperones in the process of ageing itself and in preventing and controlling age-associated diseases, the role of defective chaperones (chaperonopathies ...
Francesco Cappello, Antonino Di Stefano, Everly Conway De Macario, Alberto J.L. Macario   +3 more
openaire   +1 more source

???????????????? ?????????????????? ???????? HSP60 ???? ?????????? ???????? ?? ?????????????? ?????????? ?????? ???????????????????????? ????????????????????????????

2010
???????????????????? ?????????????????? ???????? HSP60 ???? ?????????? ???????? ?? ???????????????? ?????????????? ??????????????????, ???????????? ???? ?????????????????????? ???????????????????????????? (????????), ???? ???????????????? ???????????? ???????????????????????? ???? ?????????????? ?????????? ???? ?????????????????????????????????? ???????
openaire   +1 more source