Heat Shock Protein 60 in Cardiovascular Physiology and Diseases. [PDF]
Front Mol Biosci, 2020 Heat shock protein 60 (HSP60) is a highly conserved protein abundantly expressed in both prokaryotic and eukaryotic cells. In mammals, HSP60 has been primarily considered to reside in the mitochondria, where HSP60 and HSP10 form a complex and facilitate ...
Duan Y +5 more
europepmc +5 more sources
Heat Shock Protein 60 in Hepatocellular Carcinoma: Insights and Perspectives. [PDF]
Front Mol Biosci, 2020 Heat shock protein 60 (HSP60) is a mitochondrial chaperone that is implicated in physiological and pathological processes. For instance, it contributes to protein folding and stability, translocation of mitochondrial proteins, and apoptosis.
Hoter A, Rizk S, Naim HY.
europepmc +6 more sources
The Heat Shock Protein 60 and Pap1 Participate in the Sporothrixschenckii-Host Interaction. [PDF]
J Fungi (Basel), 2021 Sporothrixschenckii is one of the etiological agents of sporotrichosis, a worldwide-distributed subcutaneous mycosis. Its cell wall contains a glycoconjugate composed of rhamnose, mannose, glucuronic acid, and proteins, named peptidorhamnomannan, which ...
García-Carnero LC +7 more
europepmc +2 more sources
Heat shock protein 60 (HSP60) modulates adiponectin signaling by stabilizing adiponectin receptor. [PDF]
Cell Commun Signal, 2020 Adiponectin, an adipokine produced and secreted by adipocytes, is involved in regulating the development and progression of insulin resistance, diabetes, and diabetic complications.
Zhang D +9 more
europepmc +2 more sources
Detection of Chlamydial Heat Shock Protein 60 and 10 Antibody among Female Infertility. [PDF]
J Glob Infect DisIntroduction: Of the many sexually transmitted pathogens, Chlamydia trachomatis is increasingly being associated with long-term sequelae such as infertility, apart from causing genital tract infections.
Dhivya G +5 more
europepmc +2 more sources
Mechanistic study of heat shock protein 60-mediated apoptosis in DF-1 cells. [PDF]
Poult Sci: Heat shock proteins (HSP) are a group of highly conserved molecular chaperones found in various organisms and have been associated with tumorigenesis, tumor progression, and metastasis.
Li Y, Cao S, Li Y.
europepmc +2 more sources
Physiactisome: A New Nanovesicle Drug Containing Heat Shock Protein 60 for Treating Muscle Wasting and Cachexia. [PDF]
Cells, 2022 Currently, no commercially available drugs have the ability to reverse cachexia or counteract muscle wasting and the loss of lean mass. Here, we report the methodology used to develop Physiactisome—a conditioned medium released by heat shock protein 60 ...
Di Felice V +15 more
europepmc +2 more sources
Clinicopathologic significance of heat shock protein 60 as a survival predictor in breast carcinoma. [PDF]
Front OncolBackgroundWhile Heat Shock Protein 60 (HSP60) has been linked to human tumor, its clinic significance specifically in breast carcinoma is unclear. This investigation aims to retrospectively evaluate how HSP60 protein levels relate to survival outcomes ...
Wang Q, Chen S, Wu Z, Ni J.
europepmc +2 more sources
Role of heat shock protein 60 in primed and naïve states of human pluripotent stem cells. [PDF]
PLoS One, 2022 Human pluripotent stem cells (hPSCs) exist in at least two distinct states in mammals: naïve pluripotency that represents several molecular characteristics in pre-implantation epiblast and primed pluripotency that corresponds to cells poised for ...
Choi HS, Lee HM, Kim MK, Ryu CJ.
europepmc +2 more sources
Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese. [PDF]
Front Endocrinol (Lausanne), 2018 Heat shock protein 60 (HSP60) is a key protein in the crosstalk between cellular stress and inflammation. However, the status of HSP60 in diabetes and obesity is unclear.
Khadir A +6 more
europepmc +2 more sources