Results 161 to 170 of about 111,857 (291)

Tuning the Hsp70 chaperone cycle: emerging roles of GrpE-like nucleotide exchange factors in proteostasis and organelle function. [PDF]

Protein Cell
Morizono MA, Safar TV, Herzik MA.
europepmc   +1 more source

Heat shock proteins (Hsp70 and Hsp90) in neurodegeneration: pathogenic roles and therapeutic potential. [PDF]

Front Aging Neurosci
Ben Khalaf N.
europepmc   +1 more source

The human HSP70 family of chaperones: where do we stand?

Cell stress & chaperones (Print), 2016
J. Radons
semanticscholar   +1 more source

Roles of ER Membrane Protein Complex in Protein Biogenesis and Quality Control in the Lung and Beyond

Cell Proliferation, EarlyView.
The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao, Yuqing Sun, Yutao Huang, Qinghang Meng, Xinhua Lin, Wei Wei, Xiaofang Tang   +6 more
wiley   +1 more source

Involvement of L polymerase and heat shock proteins in the biogenesis of viral circular RNAs derived from respiratory syncytial virus. [PDF]

mBio
Lin M, Miao S, Yang X, Qiu Y, Mai Z, Xiao Y, Xie M, Luo Y, Ma C, Liu J, Liu Z, Yao W.   +11 more
europepmc   +1 more source

Hsp70 – a master regulator in protein degradation

FEBS Letters, 2017
M. Fernández-Fernández, Marcos Gragera, Lissette Ochoa‐Ibarrola, Lucía Quintana-Gallardo, J. Valpuesta   +4 more
semanticscholar   +1 more source

High levels of serum cholesterol increase the risk of developing vessel co‐opting tumors in colorectal cancer liver metastases

The FEBS Journal, EarlyView.
High serum cholesterol is linked to colorectal cancer liver metastases (CRCLM) subtypes with poor survival (replacement pattern). Levels of cholesterol under 4 mmol·L−1 correlated with better survival and a desmoplastic pattern subtype. Furthermore, in vivo PCSK9 inhibitor evolocumab, which lowers cholesterol, reduced liver metastases.
Amatzia Gantz, Audrey Kapelanski‐Lamoureux, Miran Rada, Lucyna Krzywon, Migmar Tsamchoe, Anastasia Tsatoumas, Stephanie K. Petrillo, Nabil G. Seidah, Anthoula Lazaris, Peter Metrakos   +9 more
wiley   +1 more source

Expression Patterns and Clinical Relevance of HSP70 and Metallothionein in Triple-Negative and Luminal A Breast Cancer: A Croatian Cohort Study. [PDF]

Cells
Bilić Knežević S, Gulić T, Grebić D, Tokić M, Avirović M, Savić-Vuković A, Marinović M, Jurišić D, Broznić D.   +8 more
europepmc   +1 more source

The ribosome‐associated complex regulates cytosolic translation upon mitoprotein‐induced stress

The FEBS Journal, EarlyView.
Defects in mitochondrial protein import trigger a stress response. The contribution of translation regulation to such a response is only partially understood. We demonstrate that the deletion of mitochondrial surface proteins (TOM70/TOM71) leads to defects in mitochondrial biogenesis and slow growth.
Jiaxin Qian, Annika Nutz, Katja Hansen, Lea Bertgen, Mirita Franz‐Wachtel, Boris Macek, Johannes M. Herrmann, Doron Rapaport   +7 more
wiley   +1 more source

RETRACTED: Wang et al. HSP70-eIF4G Interaction Promotes Protein Synthesis and Cell Proliferation in Hepatocellular Carcinoma. <i>Cancers</i> 2020, <i>12</i>, 3410. [PDF]

Cancers (Basel)
Wang M, Wei K, Qian B, Feiler S, Lemekhova A, Büchler MW, Hoffmann K.   +6 more
europepmc   +1 more source