Results 181 to 190 of about 111,857 (291)

KU80 suppresses endonuclease G activity to preserve genomic integrity

The FEBS Journal, EarlyView.
Under normal conditions, EndoG remains restricted to mitochondria and the genome remains intact. When KU80 is absent, EndoG translocates into the nucleus, where it promotes DNA fragmentation and genomic instability. Thus, this work highlights the importance of KU80 in tightly controlling EndoG localization to preserve genome stability.
Jargalan Batsaikhan, Kwang‐Hyun Park, Hae Ryung Chang, Eunyoung Jung, Myung‐Jin Kim, Jeeyoon Kang, Hyunjo Shim, Eui‐Jeon Woo, Yonghwan Kim   +8 more
wiley   +1 more source

Stress-specific NONO interactomes reveal a key role of Hsp70 chaperone activity in regulation of paraspeckle formation. [PDF]

J Cell Sci
Odonkor I, Shrestha BK, Nielsen SR, Kournoutis A, Bjørlo IE, Das Sajib S, Hedberg A, Grønset TA, Larsen KB, Bruun JA, Knutsen E, Lellahi SM, Perander M.   +12 more
europepmc   +1 more source

Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System.

Molecules and Cells, 2018
Tania Morán Luengo, Roman Kityk, M. Mayer, S. Rüdiger   +3 more
semanticscholar   +1 more source

Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley   +1 more source

Molecular Signatures of Peripheral and Central Dental Pulp Subpopulations in Response to Streptococcus mutans: A Bulk RNA‐Seq Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Aim The dental pulp is an immunologically active tissue that responds dynamically to cariogenic challenge. Peripheral pulp cells adjacent to dentine encounter bacterial stimuli earlier than cells located in the central pulp. To investigate signalling and immune interactions, this study profiled the transcriptomes of dentine‐adherent cells ...
Sandra Pohl, Maximilian L. Huber, Tobias Akamp, Andreas Rosendahl, Melanie Linnebank, Lea Schreiber, Claudia Gebhard, Nicholas Strieder, Michael Rehli, Wolfgang Buchalla, Matthias Widbiller   +10 more
wiley   +1 more source

Correlation of anxiety/depression status with stress-related markers and cancer-related fatigue in patients with colon cancer. [PDF]

World J Psychiatry
Zhao L, Jian B, Chen DH.
europepmc   +1 more source

Too hot for comfort: Elevated temperatures influence gene expression and exceed thermal tolerance of bigmouth shiners, Ericymba dorsalis

Journal of Fish Biology, EarlyView.
Abstract Environmental and associated ecosystem change may affect the persistence of fish species based on their ability to adapt to changing conditions, including decreasing flows and rising water temperatures. Exceeding the thermal tolerances of stream fish will likely result in a loss of ability to maintain metabolic processes.
Ella K. Humphrey, Jonathan J. Spurgeon, Lizbeth Bowen, Robert E. Wilson, Shannon C. Waters‐Dynes, Braxton M. Newkirk, Sarah A. Sonsthagen   +6 more
wiley   +1 more source

Synaptic Chaperone Dysfunction as a Convergent Mechanism in Neurodegenerative and Psychiatric Disorders. [PDF]

Neurosci Insights
Jean D, Li Y.
europepmc   +1 more source

Hsp70 in cancer: role of the membrane-anchored chaperone.

Cancer Letters, 2019
M. Elmallah, Marine Cordonnier, Valentin Vautrot, Gaëtan Chanteloup, C. Garrido, J. Gobbo   +5 more
semanticscholar   +1 more source

Hsp70-Antikörper [PDF]

, 2019
openaire   +1 more source