Results 241 to 250 of about 105,054 (297)

Harnessing Terminalia arjuna in Next Generation Phytomedicine: Cutting Edge Nutraceutical Trends Shaping Food and Health

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
This graphical abstract illustrates the complete translational pipeline of Terminalia arjuna in modern phytomedicine and functional food development. It is rich in key bioactive compounds like arjunolic acid, arjungenin, flavonoids, and tannins which serve as the foundation for the plant's versatile medicinal uses and offers broad therapeutic benefits ...
Ishani Banerjee, Fahika Nazeerulla, Manash Kumar Paul, Sujit Kumar Bhutia, Deblina Basu, Subhadip Mukhopadhyay   +5 more
wiley   +1 more source

Mixed-class J-domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly. [PDF]

FEBS Lett
Szlachcic A, Nillegoda NB.
europepmc   +1 more source

Understanding the Potential of Antibody‐Drug Conjugates Functionalized Engineered Exosomes in Hepatocellular Carcinoma Therapy: A Comprehensive Narrative Review

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Exosomes are naturally secreted nanovesicles with high biocompatibility, low immunogenicity, and the ability to traverse biological barriers, making them attractive theragnostic carriers. When engineered to present tumor‐specific antibodies and to deliver antibody‐drug conjugates (ADCs), they may enhance selective targeting of ...
Subham Sarkar, Avinaba Bose, Jenifer Rajak, Arup Kumar Mitra, Ajoy Kumer, Bikram Dhara   +5 more
wiley   +1 more source

CFTR functions as a tumor suppressor in adenoid cystic carcinoma and its silencing reveals an associated vulnerability involving the Hsp70 chaperone system. [PDF]

Front Oncol
Zhao G, Li L, Zhang Q, Su Y.
europepmc   +1 more source

Microbiome‐Derived Tryptophan Metabolites Regulate AhR Signaling to Restore Epithelial Barrier Integrity in Inflammatory Bowel Disease

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
The graphical abstract illustrates how microbiome‐derived indoles activate the aryl hydrocarbon receptor to restore the intestinal barrier. The picture contrasts the “leaky gut” state with the restored homeostasis achieved through AMPK, Nrf2, and IL‐22 signaling.
Mohammad Ali Mahdiabadi, Asma Moghaddam, Nafiseh Erfanian   +2 more
wiley   +1 more source

Studying the Safety of Trophectoderm Biopsy Using Visible Femtosecond Laser Pulses. [PDF]

Int J Mol Sci
Sitnikov DS, Filatov MA, Agentova VS, Il'ina IV, Ovchinnikova MA, Ovchinnikov MA, Kubekina MV, Tvorogova AV, Silaeva YY.   +8 more
europepmc   +1 more source

Extracellular Vesicles: Classification, Biological Functions, Diseases, and Therapeutic Opportunities

MedComm, Volume 7, Issue 10, October 2026.
• EV content maintains cellular homeostasis and is involved in several disease onset and progression. • miRNA export in EVs depends on: RNA‐binding proteins recognizing motif sequences and on epitranscriptomic modifications. • The disclosure of delivery mechanisms is crucial for developing personalized EV‐based therapeutic tools. ABSTRACT Extracellular
Sabrina Garbo, Francesco Marocco, Clemens Zwergel, Marco Tripodi, Cecilia Battistelli   +4 more
wiley   +1 more source

Novel Insights into the Human Hsc70 Structure by Cross-Linking Mass Spectrometry and Molecular Modeling. [PDF]

J Proteome Res
Melikov A, Viliuga V, Kavan D, Kukačka Z, Mayer MP, Novák P.   +5 more
europepmc   +1 more source

Tripterine Liposome Exerts Antitumor and Immunomodulatory Effects in Pancreatic Ductal Adenocarcinoma

MedComm, Volume 7, Issue 10, October 2026.
Tripterine liposome (TP‐lipo) exerts anti‐pancreatic ductal adenocarcinoma (PDAC) effects through direct suppression of tumor cells and modulation of the tumor microenvironment (TME). TP‐lipo induces apoptosis and inhibits the clonogenicity, migration, and invasion of KPC cells in vitro.
Lirui Tang, Yi Lin, Xueqin Jiang, Xiaohe Tian, Giuseppe Battaglia, Yuquan Wei, Wenshuang Wu, Xuemei He, Xiawei Wei   +8 more
wiley   +1 more source

In silico identification of selective cyclodecapeptide inhibitors targeting Plasmodium falciparum Grp78 chaperone. [PDF]

J Comput Aided Mol Des
Mthembu W, Odugbemi A, Muzenda FL, Rautenbach M, Zininga T.   +4 more
europepmc   +1 more source