Heat Shock Protein 70 Deficient Mice Exhibit Reduced Psoriasis-like Skin Inflammation. [PDF]
Kalantidou A +8 more
europepmc +1 more source
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed +6 more
wiley +1 more source
Autoimmunity and Periodontitis
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
Molecular chaperones at the host-virus interface: heat shock protein roles in HIV-1 and emerging insights for HIV-2 and dual infection. [PDF]
Arthur SE +8 more
europepmc +1 more source
Summary Cellular ion and pH homeostasis are crucial factors affecting and regulating metabolic reactions, protein stability, signalling and transport mechanisms. To balance intracellular ion concentrations, organisms need to constantly sense and respond to both the extracellular environment and cell compartments' requests.
Anna Santin +15 more
wiley +1 more source
Plasma Membrane Epichaperome-Lipid Interface: Regulating Dynamics and Trafficking. [PDF]
Amissah HA +8 more
europepmc +1 more source
Climate change and crop resilience: harnessing metabolomics for predicting stress tolerance
Summarised methodology for metabolite biomarker discovery and genomic targets selection for those metabolites to predict high‐throughput phenotypic and agronomic traits of interest for direct uptake in breeding programmes. Summary Global warming is driving climate change to levels not experienced since the advent of agriculture, primarily due to ...
Agyeya Pratap +3 more
wiley +1 more source
Exercise attenuates stress-related signaling as sensed by higher phosphorylation of small heat shock proteins in skeletal muscle from older individuals. [PDF]
Frankenberg NT +6 more
europepmc +1 more source
Empowerment in Obesity and Behavioral Weight‐Management Programmes: A Scoping Review
ABSTRACT In the UK, over 25% of adults are living with obesity, with disproportionately higher rates among Black adults (35%) and those in the most deprived areas (36%). Obesity is linked to increased comorbidity, mortality, stigma, and substantial annual health costs exceeding £11.4 billion.
Corinne Bolland +3 more
wiley +1 more source
Overcoming cancer drug resistance through small-molecule targeting of HSP90 and HSP70. [PDF]
Cai RD, Lin MJ, Ye QM.
europepmc +1 more source

