Results 131 to 140 of about 117,409 (314)

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti‐tumor necrosis factor alpha therapy in children

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is ...
Jonathan E. M. O'Donnell   +6 more
wiley   +1 more source

IC-IE-AKS-O: an automatic recognition method for coastal slope landslide areas

open access: yesFrontiers in Earth Science
Automatically and accurately identifying the deformation zone of coastal slope landslides is crucial for exploring the mechanism of landslides and predicting landslide disasters. To this end, this study proposes an integrated automatic recognition method
Peng Li   +15 more
doaj   +1 more source

HSV-1 infection induces protein complex formation and the association with viral gene promoters.

open access: yes, 2016
HeLa cells were infected with HSV-1 at 10 MOI for times as indicated. The samples were then processed for detection of protein association by immunoprecipitation assay, for protein co-localization by immunostaining, for protein-DNA interactions by a ...
Ke Ren (34504)   +8 more
core   +1 more source

Image‐based and biochemical multimodal phenotyping for explainable classification of chia (Salvia hispanica L.) genotypes

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND This study developed an explainable machine learning framework integrating morphological, color, and biochemical characteristics for classifying chia (Salvia hispanica L.) genotypes. A dataset was assembled from 1200 seed images spanning four genotypes, from which 17 morphological and color features were extracted.
Sevim Akcura   +3 more
wiley   +1 more source

HSV-1 ICP27 causes aberrant pre-mRNA processing of cellular transcripts in infected cells in a gene/sequence specific manner.

open access: yes, 2019
RNA-seq data from wild-type HSV or ICP27 deletion mutant infected HEK- HEK-293 cells were aligned to the human genome HG19 reference sequence using CLC Genomics Workbench. Representative genes for which co-transcriptional pre-mRNA processing is modulated
Amita Patel (848633)   +2 more
core   +1 more source

Image Vividness Changes due to White‐Boosting on WOLED Display

open access: yesJournal of the Society for Information Display, EarlyView.
White‐Boosting is a display technique for RGBW WOLED panels that increases peak brightness. This study investigated its effect on perceived image vividness using paired‐comparison experiments. Across three psychophysical experiments, higher White‐Boosting consistently enhanced perceived vividness.
Woojae Jung   +3 more
wiley   +1 more source

HSV-1 culture of NK cells reduces responsiveness to K562 stimulation and infection blocks IFN-γ expression.

open access: yes, 2019
PBMCs were mock cultured, exposed to HSV-1, or HSV-1 infected for 1 day and stimulated as specified for flow cytometry analysis of NK cells (viable CD3–CD56+ cells). (A) SPICE pie charts show the proportion of responses to different stimuli (listed left)
Tiffany Ann Russell (6837791)   +7 more
core   +1 more source

Juvenile Gangrenous Vasculitis of the Scrotum or Scrotum Lipschütz Ulcers

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Lipschütz genital ulcers are traditionally described in adolescent females and often linked to acute viral infections. Their male counterpart remains poorly characterised. We report a 59‐year‐old man with sudden onset of unilateral necrotic ulcers on the scrotum and inguinal region following a brief febrile episode and mild pharyngitis ...
Francesco Bellinato   +2 more
wiley   +1 more source

Bevacizumab‐Associated Eczema Herpeticum in Metastatic Ovarian Carcinoma: A Case Report

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Eczema herpeticum (EH) is a rare but potentially life‐threatening cutaneous infection caused by herpes simplex virus (HSV), classically associated with atopic dermatitis. Its occurrence in oncology patients receiving anti‐angiogenic targeted therapy and cytotoxic chemotherapy is exceedingly uncommon.
Mandeep Dutta Joshi   +6 more
wiley   +1 more source

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