Targeting Genome Maintenance Defects of Cancers Using Chain‐Terminating Nucleoside Analogs
Cancer Science, EarlyView.Nucleoside analogs interfere with DNA replication either by their chain‐terminating properties or by serving as DNA damage on the template. The genome maintenance pathways required to maintain cellular tolerance to each nucleoside analog vary depending on the drug.
Ryotaro Kawasumi +2 more
wiley +1 more source
832. Intrapleural Administration of Third Generation Oncolytic HSV-1 (G47Δ) Is Highly Efficacious in Orthotopic Malignant Pleural Mesothelioma Models [PDF]
, 2010 openalex +1 more source
Image‐Based Spatio‐Temporal Interpolation for Split Rendering
Computer Graphics Forum, EarlyView.Abstract Low‐powered devices – such as small form factor head‐mounted displays (HMDs) – struggle to deliver a smooth and high‐quality viewing experience, due to their limited power and rendering capabilities. Cloud rendering attempts to solve the quality issue, but leads to prohibitive latency and bandwidth requirements, hindering use with HMDs over ...
M. Steiner +4 more
wiley +1 more source
Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling
Cell Proliferation, EarlyView.This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava +9 more
wiley +1 more source
Multifunctional Tannic Acid/Silver Nanoparticle-Based Mucoadhesive Hydrogel for Improved Local Treatment of HSV Infection: In Vitro and In Vivo Studies [PDF]
, 2018 Emilia Szymańska +8 more
openalex +1 more source
HSV-1 Triggers an Antiviral Transcriptional Response during Viral Replication That Is Completely Abrogated in PKR−/− Cells [PDF]
, 2023 Rosamaria Pennisi +1 more
openalex +1 more source
Cryptococcid Sweet Syndrome in the Setting of Hydralazine‐Induced ANCA Vasculitis: A Case Report
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Acute febrile neutrophilic dermatosis, also known as Sweet syndrome, is an inflammatory skin condition characterized by the rapid onset of painful, erythematous plaques or nodules with neutrophilic infiltrate on histology. Rarely, acellular bodies surrounded by vacuolated spaces have been noted within the neutrophilic infiltrate, mimicking ...
Jenna Vroman +4 more
wiley +1 more source
Developmental Medicine &Child Neurology, EarlyView.Abstract Aim To evaluate the relationship between Preverbal Visual Assessment (PreViAs) results and cerebral visual impairment (CVI) diagnosis. Method This single‐center retrospective chart review included children who completed a CVI interdisciplinary clinic or occupational therapy vision evaluation between May 2018 and May 2023 and had a completed ...
Karen L. Harpster +5 more
wiley +1 more source