Results 161 to 170 of about 117,409 (314)

16S/18S metabarcoding versus culture for aetiological assessment in infectious keratitis: A prospective paired‐sample study

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Infectious keratitis (IK) is a vision‐threatening condition with diverse microbial aetiologies, yet conventional culture‐based diagnostics often have limited sensitivity. We investigated whether 16S/18S rRNA amplicon‐based next‐generation sequencing (NGS) can enhance aetiological assessment when used alongside standard microbiological ...
Sandra M. Skovdal   +6 more
wiley   +1 more source

Editorial: Oncolytic virotherapy

open access: yesFrontiers in Molecular Biosciences, 2023
Ahmed Majeed Al-Shammari   +2 more
doaj   +1 more source

Syncytium-forming HSV-1 in cancer gene therapy: From molecular mechanisms to clinical translation. [PDF]

open access: yesVirulence
Zhao X   +7 more
europepmc   +1 more source

p‑Terphenyls as Anti-HSV-1/2 Agents from a Deep-Sea-Derived Penicillium sp.

open access: yes
Guided by Global Natural Products Social molecular networking, two p-terphenyl derivatives and one 4,5-diphenyl-2-pyrone analogue, peniterphenyls A–C (1–3), together with five known p-terphenyl derivatives (4–8) and sulochrin (9), were obtained from a ...
Xin Qi (177590)   +12 more
core   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

open access: yesBritish Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu   +6 more
wiley   +1 more source

Precision virotherapy for IDH-mutant astrocytoma. [PDF]

open access: yesMol Ther Oncol
Panagioti E   +4 more
europepmc   +1 more source

Image‐Based Spatio‐Temporal Interpolation for Split Rendering

open access: yesComputer Graphics Forum, EarlyView.
Abstract Low‐powered devices – such as small form factor head‐mounted displays (HMDs) – struggle to deliver a smooth and high‐quality viewing experience, due to their limited power and rendering capabilities. Cloud rendering attempts to solve the quality issue, but leads to prohibitive latency and bandwidth requirements, hindering use with HMDs over ...
M. Steiner   +4 more
wiley   +1 more source

Edge‐preserving noise for diffusion models

open access: yesComputer Graphics Forum, EarlyView.
Abstract Classical diffusion models typically rely on isotropic Gaussian noise, treating all regions uniformly and overlooking structural information important for high‐quality generation. We introduce an edge‐preserving diffusion process that generalizes isotropic models via a hybrid noise scheme with an edge‐aware scheduler that smoothly transitions ...
Jente Vandersanden   +3 more
wiley   +1 more source

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