MyD88‐Family Adaptors: Compartmentalised Signalling and Non‐Immune Functions
MyD88‐family adaptors coordinate receptor‐ and compartment‐specific innate immune signalling across plasma membrane and endosomal pathways. At the plasma membrane, TIRAP/MAL supports MyD88‐dependent signalling downstream of TLR2 and TLR4, whereas endosomal TLR7, TLR8 and TLR9 recruit MyD88 directly.
Seshu Vardhan Pothabathula +6 more
wiley +1 more source
Loss of Akt3 enhances antiviral immunity while disrupting corneal homeostasis during ocular HSV-1 infection. [PDF]
Kadam R +6 more
europepmc +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katharina A. Kälber +3 more
wiley +1 more source
Spectral Transforms as a Tool to Optimize Digital Phenotyping in Biological Images
ABSTRACT Modern livestock breeding has mastered genotyping. Genome‐wide association studies, genomic selection, and SNP arrays enable genetic merit prediction at lower cost. However, phenotyping remains the bottleneck, as manual measurement is slow, expensive, subjective, and unable to capture spatial or temporal trait organization. Digital phenotyping
Joseane Padilha +2 more
wiley +1 more source
A case of neonatal herpes simplex virus type 2 encephalitis with <i>TLR3</i> gene mutation and literature review. [PDF]
Li X, Chen Y, Deng C, Wang D, Qiu J.
europepmc +1 more source
Implementation of a molecular assay for Treponema pallidum detection in the management of syphilis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Valeria Gaspari +4 more
wiley +1 more source
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra +5 more
wiley +1 more source
In Vivo Activity of Antimicrobial Peptoid Oligomers against HSV-1 in a Mouse Model of Herpes Labialis. [PDF]
Figgins EL +10 more
europepmc +1 more source
Darier disease—A review highlighting new insights from the Darier Disease International Task Force
This review provides a global, clinically focused overview of DD, detailing cutaneous and extracutaneous manifestations, disease classification and severity scoring. It emphasizes early recognition, multidisciplinary management and practical guidance for dermatologists to apply evidence‐based care in diverse skin phototypes. Abstract Darier disease (DD)
Sofia Labbouz +49 more
wiley +1 more source
Expert consensus on oral management in autoimmune bullous diseases, erythema multiforme and SJS/TEN
This international Delphi study achieved expert consensus on 58 statements guiding the management of oral involvement in autoimmune bullous diseases, erythema multiforme and SJS‐TEN. The recommendations emphasize multidisciplinary care, oral hygiene and tailored topical, systemic and inpatient oral management.
Shalini Nayee +39 more
wiley +1 more source

