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HSV Mutagenesis

2003
Herpes genomes are large and complex, with many interactions among herpes encoded proteins, herpes DNA and RNA, and the host cell. These interactions begin as the virus enters the cell, and continue as the decision for latency or lytic replication is made.
openaire   +2 more sources

Anterograde transport of HSV-1 and HSV-2 in the visual system

Brain Research Bulletin, 1992
The anterograde spread of herpesvirus in the visual system subsequent to retinitis has been observed clinically. We compared the ability of two well-studied Herpes simplex virus (HSV) strains to be transported in the anterograde direction in the hamster visual system: strain McIntyre, representing HSV-1, and strain 186, representing HSV-2. Intravitreal
David Bernstein   +2 more
exaly   +3 more sources

Analysis of HSV Polypeptides

2003
Lytic infection by herpes simplex virus (HSV) efficiently inhibits the synthesis of most cellular proteins while a large number of viral proteins is produced, including a host shut off protein (1-3). The inhibitory effect of the protein obviously needs a certain period of time to be fully efficient, but some cellular proteins involved in virus ...
L, Haarr, N, Langeland
openaire   +2 more sources

Oncolytic Virotherapy by HSV

2018
Oncolytic virotherapy is a kind of antitumor therapy using viruses with natural or engineered tumor-selective replication to intentionally infect and kill tumor cells. An early clinical trial has been performed in the 1950s using wild-type and non-engineered in vitro-passaged virus strains and vaccine strains (first generation oncolytic viruses ...
Daisuke, Watanabe, Fumi, Goshima
openaire   +2 more sources

HSV and the CNS

The Neuroscientist, 1996
Herpes simplex virus encephalitis (HSVE) is an encephalitis with a predelection for the temporal lobes and related structures that is caused by HSV-1 or HSV-2. Because HSV has many properties that would be ideal for a gene transfer vector targeting the nervous system, an understanding of HSVE is of experimental, as well as clinical, importance to ...
Uta Meyding-Lamadé, Wolfram Lamadé
openaire   +1 more source

HSV

The Global Library of Women's Medicine, 2023
Isabel do Val   +2 more
openaire   +1 more source

HSV Entry and Spread

2003
This chapter deals with assays commonly used to follow herpes simplex virus type 1 (HSV-1) entry into and spread between cells in tissue culture These are complex processes, known to involve several of the 20 or more HSV-encoded membrane proteins (see refs. 1 and 2 for recent reviews). HSV entry is mediated by a number of proteins on the surface of the
openaire   +2 more sources

Increase of genital HSV-1 and mixed HSV-1 and HSV-2 infection in Bangkok, Thailand.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2006
From January 1998 to December 2004, 207 out of 1125 samples were HSV isolation positive and typed. Two groups of patients, Thai and foreigner, as well as site of infection, non-genital and genital area, were identified. The prevalence of non-genital HSV-1 infection from 27 samples of Thai patients was 81.84%.
Parvapan, Bhattarakosol   +3 more
openaire   +1 more source

“Non-Essential” Proteins of HSV-1 with Essential Roles In Vivo: A Comprehensive Review

Viruses, 2021
Maria Kalamvoki   +2 more
exaly  

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