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Antiviral Research, 2004
Viral shedding of HSV occurs frequently in infected individuals. HSV is shed asymptomatically from multiple anatomical sites and shedding, like exposure, is a significant risk for transmission. However, the relationship between shedding frequency, viral titer and transmission is unknown. HSV-2 shedding is affected by the site and time since acquisition
S L, Sacks +10 more
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Viral shedding of HSV occurs frequently in infected individuals. HSV is shed asymptomatically from multiple anatomical sites and shedding, like exposure, is a significant risk for transmission. However, the relationship between shedding frequency, viral titer and transmission is unknown. HSV-2 shedding is affected by the site and time since acquisition
S L, Sacks +10 more
openaire +2 more sources
Seroprevalence of HSV-1 and HSV-2 in Barbados
Medical Microbiology and Immunology, 2004Type-specific enzyme-linked immunosorbent assays, based upon recombinant glycoprotein G (gG), were used to detect antibodies to HSV-1 and HSV-2, in a small Caribbean island population. A blinded serosurvey was performed on samples from 184 blood donors, 122 pregnant women, and 120 HIV-positive patients. The seroprevalence of HSV-1 and HSV-2 was 81% and
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Journal of Infectious Diseases, 2013 BACKGROUND: Daily suppressive therapy with valacyclovir reduces risk of sexual transmission of herpes simplex virus type 2 (HSV-2) in HSV-2-serodiscordant heterosexual couples by 48%.
Amalia S Magaret +2 more
exaly +2 more sources
HSV: immunopathological aspects of HSV infection
2007Introduction “What is food to one man is bitter poison to others” Lucretius De Rerum Natura (50BCE) Foreign material entering multicellular organisms triggers a range of defense reactions which, when successful, subjugates and removes the invaders.
Kaustuv Banerjee, Barry T. Rouse
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Antiviral Research, 2004
A number of important risk factors for the acquisition of HSV-2 have been established including female gender, black or Hispanic ethnic origin, HIV infection, age, and increased number of sexual partners. Transmission is influenced by a number of biological factors such as sexual behavior, use of condoms, duration of relationships, and knowledge of a ...
S L, Sacks +10 more
openaire +2 more sources
A number of important risk factors for the acquisition of HSV-2 have been established including female gender, black or Hispanic ethnic origin, HIV infection, age, and increased number of sexual partners. Transmission is influenced by a number of biological factors such as sexual behavior, use of condoms, duration of relationships, and knowledge of a ...
S L, Sacks +10 more
openaire +2 more sources
2003
Herpes genomes are large and complex, with many interactions among herpes encoded proteins, herpes DNA and RNA, and the host cell. These interactions begin as the virus enters the cell, and continue as the decision for latency or lytic replication is made.
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Herpes genomes are large and complex, with many interactions among herpes encoded proteins, herpes DNA and RNA, and the host cell. These interactions begin as the virus enters the cell, and continue as the decision for latency or lytic replication is made.
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2003
Lytic infection by herpes simplex virus (HSV) efficiently inhibits the synthesis of most cellular proteins while a large number of viral proteins is produced, including a host shut off protein (1-3). The inhibitory effect of the protein obviously needs a certain period of time to be fully efficient, but some cellular proteins involved in virus ...
L, Haarr, N, Langeland
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Lytic infection by herpes simplex virus (HSV) efficiently inhibits the synthesis of most cellular proteins while a large number of viral proteins is produced, including a host shut off protein (1-3). The inhibitory effect of the protein obviously needs a certain period of time to be fully efficient, but some cellular proteins involved in virus ...
L, Haarr, N, Langeland
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Anterograde transport of HSV-1 and HSV-2 in the visual system
Brain Research Bulletin, 1992The anterograde spread of herpesvirus in the visual system subsequent to retinitis has been observed clinically. We compared the ability of two well-studied Herpes simplex virus (HSV) strains to be transported in the anterograde direction in the hamster visual system: strain McIntyre, representing HSV-1, and strain 186, representing HSV-2. Intravitreal
R B, Norgren +5 more
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