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Molecular epidemiology of HTLV-2 infection among intravenous drug users in Spain
Journal of Clinical Virology, 2005HTLV-2 infection is prevalent among intravenous drug users (IDUs), which often are coinfected with HIV-1. Two main subtypes, HTLV-2a and -2b, have been described among European IDUs, with a characteristically geographic distribution: IIa in northern Europe and IIb in the south.
Carlos, Toro +7 more
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Rétrovirus humains HTLV-1 et HTLV-2
EMC - Maladies infectieuses, 2004Resume Human T cell leukemia/lymphoma virus type 1 (HTLV-1), premier retrovirus oncogene decouvert chez l'homme en 1980, possede, outre les genes gag, pol et env codant les proteines structurales et enzymatiques du virus, une region unique (nommee pX) codant les proteines regulatrices Tax et Rex.
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FISIOPATOLOGIA E EPIDEMIOLOGIA DO HTLV-1 E HTLV-2: UMA REVISÃO SISTEMÁTICA
REVISTA FIMCA, 2022Os vírus linfotrópicos de células T humanas são altamente associados à oncogenicidade, classificados em quatro tipos (HTLV-1, 2, 3 e 4) dos quais os mais relevantes são HTLV-1 e HTLV-2 devido a maior associação ao desenvolvimento clínico crônico da patologia influenciando a oncogênese nos seus hospedeiros.
Alan Kennedy Braga Ferreira +4 more
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Hematologic hints of HTLV-2 in US blood donors
Blood, 2008The HOST investigators have maintained a multiregional and longitudinal survey of donors infected with HTLV-I and HTLV-II for over 14 years. The survey has provided extremely valuable information regarding the long-term consequences of asymptomatic infection with HTLV-I or HTLV-II.[1][1],[2][2 ...
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NK cells constitute a major reservoir of HTLV‐2 infection in vivo
The FASEB Journal, 2008HTLV‐2 is a deltaretrovirus, possibly associated with neurological manifestations. Initially believed to be restricted to CD8+ lymphocytes, the virus has been shown to infect also CD4+ T‐cells and B cells. Here we show for the first time that HTLV‐2 also infects NK cells in vivo .
Andre L A Oliveira +5 more
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Long Terminal Repeat Sequence Analysis of HTLV-2 Molecular Variants Identified in Southern Brazil
AIDS Research and Human Retroviruses, 2010In Brazil, human T-lymphotropic virus type 2 (HTLV-2) is endemic in Amerindians and epidemic in intravenous drug users (IDUs). The long terminal repeat (LTR) is the most divergent genomic region of HTLV-2, therefore useful to characterize subtypes. Nucleotide sequence and restriction fragment length polymorphism (RFLP) analysis of LTR genomic segments ...
Mariana Cavalheiro, Magri +4 more
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Evaluation of the New Multi-HTLV Serological Assay: Improvement for HTLV-2 Detection
AIDS Research and Human RetrovirusesDespite the accuracy of confirmatory tests for the diagnosis of human T cell lymphotropic virus (HTLV), inconclusive or false-negative results still occur when diagnosing human T cell lymphotropic virus type 2 (HTLV-2)-positive patients. The goal of this study was to evaluate the sensitivity and accuracy of a confirmatory immunoassay, the Multi-HTLV ...
Victor Ângelo Folgosi +9 more
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Human T-Cell Leukemia Virus Type 2 (HTLV-2) Biology and Pathogenesis
2011Human T-cell leukemia viruses (HTLV) type 1 (HTLV-1) and type 2 (HTLV-2) are highly related complex retroviruses that have been studied intensely for nearly three decades because of their capacity to transform primary human T-lymphocytes, their association with neuropathology, and/or neoplasia.
Rami Doueiri, Patrick L. Green
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Stability of HTLV-2 antisense protein is controlled by PML nuclear bodies in a SUMO-dependent manner
Oncogene, 2018Louise Dubuisson +11 more
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Mielopatía en paciente coinfectado por VIH y HTLV-2
Revista Clínica Española, 2010R. Ramírez Montesinos +3 more
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