Results 81 to 90 of about 22,246,700 (213)

Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation

open access: yesThe FEBS Journal, EarlyView.
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley   +1 more source

Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil

open access: yesMemorias do Instituto Oswaldo Cruz, 2014
Human T-cell lymphotropic virus (HTLV) may impact the clinical course of tuberculosis (TB). Both infections are highly endemic in Brazil. The aim of this study was to assess the prevalence of HTLV-1/2 in TB patients in Central-West Brazil and to perform ...
Aline Garcia Kozlowski   +7 more
doaj   +1 more source

Association between human papillomavirus and human T-lymphotropic virus in indigenous women from the Peruvian Amazon. [PDF]

open access: yesPLoS ONE, 2012
No association between the Human T-cell lymphotropic virus (HTLV), an oncogenic virus that alters host immunity, and the Human Papillomavirus (HPV) has previously been reported.
Magaly M Blas   +6 more
doaj   +1 more source

SOROPREVALÊNCIA DO VÍRUS LINFOTRÓPICO DE CÉLULAS T HUMANAS (HTLV1/2) EM DOADORES DE SANGUE DO INSTITUTO DE HEMATOLOGIA E HEMOTERAPIA DO AMAPÁ

open access: yesHematology, Transfusion and Cell Therapy, 2023
Introdução: O Vírus linfotrópicos de células T Humanas 1 e 2 (HTLV-1, HTLV-2) pertencem à família Retroviridae , gênero Deltaretrovirus. Possuem semelhantes mecanismos de ação com tropismo por linfócitos T e uma associação com raras doenças ...
RF Frazão   +9 more
doaj   +1 more source

Human T Cell Lymphotrophic Virus 1 After Transplantation: What Is the Risk of Recipient Disease? [PDF]

open access: yes, 2012
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/92115/1/j.1600-6143.2012.04041.x ...
Kaul, D. R.
core   +1 more source

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

open access: yesImmunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu   +24 more
wiley   +1 more source

A preclinical model for the ATLL lymphoma subtype with insights into the role of microenvironment in HTLV-1-mediated lymphomagenesis [PDF]

open access: yes, 2018
\uef7f View references (83) Adult T cell Leukemia/Lymphoma (ATLL) is a mature T cell malignancy associated with Human T cell Leukemia Virus type 1 (HTLV-1) infection.
Adriana Mattiolo   +8 more
core   +2 more sources

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

open access: yesJournal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag   +6 more
wiley   +1 more source

HTLV-2 in Central Africa: HTLV-2 subtype B strains similar to those found in Amerindian tribes are endemic in Bakola Pygmies from south Cameroon but not in surrounding Bantus and Baka Pygmies [PDF]

open access: yes, 2011
International audienceBackground:Presence and origin of endemic foci of HTLV-2 infection in Africa remain a matter of debate.Material and methods:To better appreciate the epidemiological and molecular determinants of HTLV-2 infection in Central Africa ...
Afonso, Philippe   +12 more
core   +6 more sources

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