Results 81 to 90 of about 33,805 (209)

Human T-lymphotropic virus 1/2 infection among prisoners of a major penitentiary complex of Goiás State, Central-West Brazil

open access: yesFrontiers in Public Health
IntroductionStudies on human T-lymphotropic virus 1/2 (HTLV-1/2) infection are scarce in incarcerated population. Therefore, this study estimated the prevalence of HTLV-1/2 infection among prisoners of the major penitentiary complex of Goiás State ...
Michele Tiemi Okita   +7 more
doaj   +1 more source

Comparative host protein interactions with HTLV-1 p30 and HTLV-2 p28: insights into difference in pathobiology of human retroviruses

open access: yesRetrovirology, 2012
Background Human T lymphotropic virus type-1 (HTLV-1) and type 2 (HTLV-2) are closely related human retroviruses, but have unique disease associations.
Doueiri Rami   +5 more
doaj   +1 more source

Comparative studies between HTLV-1 and HTLV-2 function and pathobiology

open access: yes, 2015
Human T-cell leukemia viruses type 1 and 2 (HTLV-1 and HTLV-2) share a common genetic organization, expression strategy and ability to infect and immortalize T-cells in vitro; however, HTLV-1 and HTLV-2 are strikingly different in terms of clinical impact. HTLV-1 is recognized as the aetiological agent of adult T-cell leukemia/lymphoma (ATLL), and HTLV-
Bertazzoni, Umberto, Bex, Françoise
openaire   +3 more sources

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro   +6 more
wiley   +1 more source

Interplay between the HTLV-2 Tax and APH-2 proteins in the regulation of the AP-1 pathway

open access: yesRetrovirology, 2012
Background In contrast with human T-cell leukemia virus type 1 (HTLV-1) that causes ATL (adult T-cell leukemia), HTLV-2 has not been causally linked to malignant disease.
Marban Céline   +4 more
doaj   +1 more source

Dynamic Allostery in T Cell Receptor Specificity: A Role for Peptides and MHC Polymorphisms in Allosterically Tuning Immune Recognition

open access: yesBioEssays, Volume 48, Issue 3, March 2026.
Along with peptides, MHC polymorphisms allosterically tune peptide energy landscapes, altering conformational dynamics and T cell receptor recognition. This dynamic allostery mechanism explains how subtle polymorphic differences drive differential immune specificity across individuals and populations.
Bassant Eldaly, Brian M. Baker
wiley   +1 more source

Surveillance of human retroviruses in blood samples from patients with hepatitis B and C in São Paulo, Brazil

open access: yesRevista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION Human retroviruses and the hepatitis B and C viruses (HBV and HCV, respectively) share routes of transmission; thus, coinfections occur and could alter subsequent disease outcomes.
Adele Caterino-de-Araujo   +5 more
doaj   +1 more source

Mechanistic role of GNE‐987 targeting BRD4‐HCP5 axis in pediatric T‐cell acute lymphoblastic leukemia

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 1, March 2026.
Abstract This study aims to explore the mechanism of action of the Bromodomain‐containing protein 4 (BRD4) inhibitor GNE‐987 in the treatment of pediatric T‐cell Acute Lymphoblastic Leukemia (T‐ALL), focusing on its effect in inhibiting T‐ALL cell proliferation by activating the HLA Complex P5 (HCP5) Super‐enhancer.
Xu Sang   +6 more
wiley   +1 more source

Helminths as architects of trained tolerance: implications for human health

open access: yesClinical &Translational Immunology, Volume 15, Issue 3, 2026.
Abstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Quinn Moroz   +2 more
wiley   +1 more source

Work-Related Human T-lymphotropic Virus 1 and 2 (HTLV-1/2) Infection: A Systematic Review [PDF]

open access: gold, 2021
Angela Stufano   +6 more
openalex   +1 more source

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