Results 71 to 80 of about 34,765 (207)
Revista do Instituto de Medicina Tropical de São Paulo, 2009 Epidemiological studies conducted in Peru disclosed HTLV-1 to be prevalent in different ethnic groups, and found HTLV-2 in some Amazonian Indians and in men who have sex with men.
Nadia Carmela Santos Quispe +3 more
doaj +1 more source
The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators [PDF]
, 2013 The activation of CD4(+) T helper cells is strictly dependent on the presentation of antigenic peptides by MHC class II (MHC-II) molecules. MHC-II expression is primarily regulated at the transcriptional level by the AIR-1 gene product CIITA (class II ...
Abdallah, R. +3 more
core +2 more sources
British Journal of Haematology, EarlyView.Summary Although adult T‐cell leukaemia/lymphoma (ATL) has a higher burden in certain world regions, outcomes have not been directly compared across regions. We conducted a multicentre cohort study comparing the distribution of ATL subtypes and overall survival (OS) across 1090 adults (≥18 years) diagnosed with ATL during 2000–2023 in Japan (n = 366 ...
Bryan Valcarcel +31 more
wiley +1 more source
Hematology, Transfusion and Cell Therapy, 2023 Introdução: O Vírus linfotrópicos de células T Humanas 1 e 2 (HTLV-1, HTLV-2) pertencem à família Retroviridae , gênero Deltaretrovirus. Possuem semelhantes mecanismos de ação com tropismo por linfócitos T e uma associação com raras doenças ...
RF Frazão +9 more
doaj +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy with a poor prognosis and limited therapeutic options. ATL cells exhibit aberrant surface glycosylation patterns resulting from dysregulated glycosyltransferase expression, representing a potentially tumor‐specific therapeutic target.
Yuichiro Uchida +7 more
wiley +1 more source
Human T-Lymphotropic viruses evolution possibly explained by primate deltaretrovirus geographical segregation [PDF]
, 2008 The primate T cell lymphotropic virus group comprises pathogenic and apathogenic agents found in human and simian hosts. Up to date, three types of the simian T cell lymphotropic virus/STLV and four types of the human T cell lymphotropic virus/HTLV have ...
Casseb, Jorge Simão do Rosário +1 more
core
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala +14 more
wiley +1 more source
HIV-1/HTLV Co-Infection: a Survey of Molecular Basis with Clinical Studies [PDF]
Patient Safety and Quality Improvement Journal, 2017 Human immunodeficiency virus type-1 (HIV–1) and human T-cell leukemia virus (HIV-1/HTLV) co-infection is a serious health problem worldwide, especially in endemic areas and vulnerable subjects like intravenous drug abusers.
Marzieh Saberi, Ashraf Tavanaii sani
doaj +1 more source
Frontiers in Medicine, 2022 Human T lymphotropic virus 1 (HTLV-1) is a public health issue for most countries and imposes important consequences on patients' health and socioeconomic status. Brazil is one of the global leaders of the public health response to these viruses.
Angelica Espinosa Miranda +7 more
doaj +1 more source
ADAR1 restricts LINE-1 retrotransposition [PDF]
, 2016 Adenosine deaminases acting on RNA (ADARs) are involved in RNA editing that converts adenosines to inosines in double-stranded RNAs. ADAR1 was demonstrated to be functional on different viruses exerting either antiviral or proviral effects.
Antonioni, Ambra +9 more
core +2 more sources