Results 51 to 60 of about 17,692,958 (217)

2 (HTLV‐1/2) in South African blood donors [PDF]

open access: yes, 2019
International audienceBackground and objectivesDonated blood is not currently screened for human T‐cell lymphotropic virus (HTLV) in South Africa.
Hlela, Carol   +28 more
core   +1 more source

HTLV-1 and HTLV-2: highly similar viruses with distinct oncogenic properties [PDF]

open access: yesFrontiers in Microbiology, 2014
HTLV-1 and HTLV-2 share broad similarities in their overall genetic organization and expression pattern, but they differ substantially in their pathogenic properties. This review outlines distinctive features of HTLV-1 and HTLV-2 that might provide clues to explain their distinct clinical outcomes.
CIMINALE, VINCENZO   +3 more
openaire   +3 more sources

HTLV-1 and HIV/HTLV-1 prevalence distribution by sex and age class.

open access: yes, 2022
The figure shows the overall prevalence of infection by age group and the prevalence of infection by sex: A) In the HIV-1/HTLV-1 coinfected population; B) In the general population at the same place.
Jeanne Sica (686072)   +10 more
core   +1 more source

The Association of Increase of Human T-Cell Leukemia Virus Type-1 (HTLV-1) Proviral Load (PVL) With Infection in HTLV-1-Positive Patients With Rheumatoid Arthritis: A Longitudinal Analysis of Changes in HTLV-1 PVLs in a Single Center Cohort Study

open access: yesFrontiers in Immunology, 2022
ObjectiveWe evaluated changes of HTLV-1 proviral loads (PVLs) during treatment for rheumatoid arthritis (RA) and investigated whether these changes affect the clinical course in HTLV-1-positive RA patients.MethodsA total of 41 HTLV-1-positive RA patients
Naoki Iwamoto   +12 more
doaj   +1 more source

History of the discoveries of the first human retroviruses: HTLV-1 and HTLV-2 [PDF]

open access: yesOncogene, 2005
HTLV-1 was discovered in the US in 1979, and published in 1980. This was rapidly followed by four additional reports in early 1981 describing additional isolates, characterization of some of the HTLV-1 proteins, serological assays for specific antibodies indicative of HTLV-1 infection, and evidence for integrated DNA proviruses in infected cells.
openaire   +2 more sources

No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms

open access: yes, 2007
Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Hummel, Michael   +9 more
core   +1 more source

HTLV-1, HTLV-2, and associated diseases

open access: yes, 2010
Abstract Human T-cell leukaemia virus (HTLV)-1 and HTLV-2 belong to the genus Deltaretrovirus of the family Retroviridae. They only infect humans, produce a lifelong infection, and can be transmitted from mother to child, through sexual intercourse, and via cellular blood components and organ transplantation.
Verdonck, K., Gotuzzo, E.
openaire   +3 more sources

The antisense protein of HTLV-2 positively modulates HIV-1 replication [PDF]

open access: yesRetrovirology, 2014
Unlike HTLV-1, HTLV-2 does not induce leukemia and has been tentatively associated with an HTLV-1-associated myelopathy-like disorder. It has been reported that HTLV-2/HIV-1 co-infected patients progress less rapidly to AIDS than HIV-1-infected individuals.
Torresilla, Cynthia   +6 more
openaire   +5 more sources

HTLV-1/2 proviral load by sex and age among rural population in Gabon, central Africa.

open access: yes, 2018
Rectangle: Average magnitude of HTLV1/2 proviral load; Line: Median proviral load; Bar: Standard deviation. HTLV-1/2 proviral load was measured by a multiplex real-time PCR assay involving a molecular beacon probe for simultaneous detection ...
Maria Makuwa (131491)   +6 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

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