Results 31 to 40 of about 33,380 (132)

Trends in the prevalence and distribution of HTLV-1 and HTLV-2 infections in Spain

Virology Journal, 2012
Background Although most HTLV infections in Spain have been found in native intravenous drug users carrying HTLV-2, the large immigration flows from Latin America and Sub-Saharan Africa in recent years may have changed the prevalence and distribution of ...
Treviño Ana, Aguilera Antonio, Caballero Estrella, Benito Rafael, Parra Patricia, Eiros Jose M, Hernandez Araceli, Calderón Enrique, Rodríguez Manuel, Torres Alvaro, García Juan, Ramos Jose, Roc Lourdes, Marcaida Goitzane, Rodríguez Carmen, Trigo Matilde, Gomez Cesar, de Lejarazu Raul, de Mendoza Carmen, Soriano Vincent   +19 more
doaj   +1 more source

The Association of Increase of Human T-Cell Leukemia Virus Type-1 (HTLV-1) Proviral Load (PVL) With Infection in HTLV-1-Positive Patients With Rheumatoid Arthritis: A Longitudinal Analysis of Changes in HTLV-1 PVLs in a Single Center Cohort Study

Frontiers in Immunology, 2022
ObjectiveWe evaluated changes of HTLV-1 proviral loads (PVLs) during treatment for rheumatoid arthritis (RA) and investigated whether these changes affect the clinical course in HTLV-1-positive RA patients.MethodsA total of 41 HTLV-1-positive RA patients
Naoki Iwamoto, Naoki Iwamoto, Takeshi Araki, Ayaka Umetsu, Ayuko Takatani, Toshiyuki Aramaki, Kunihiro Ichinose, Kunihiro Ichinose, Kaoru Terada, Naoyuki Hirakata, Yukitaka Ueki, Atsushi Kawakami, Katsumi Eguchi   +12 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Glycoengineered Recombinant Alpha1‐Antitrypsin Results in Comparable In Vitro and In Vivo Activities to Human Plasma‐Derived Protein

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Alpha‐1‐antitrypsin (A1AT) is a multifunctional, clinically important, high‐value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes, graft‐versus‐host disease, cystic fibrosis, and various viral infections. Currently, the only U.S. food and drug administration‐approved treatment for
Frances Rocamora, Chen‐Lin Hsieh, Sanne Schoffelen, Johnny Arnsdorf, Eric A. Toth, Abdul S. Yunus, Thomas E. Cleveland IV, Sara Petersen Bjørn, Mina Ying Min Wu, Noel G. McElvaney, Bjørn Gunnar Rude Voldborg, Thomas R. Fuerst, Nathan E. Lewis   +12 more
wiley   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Human T-lymphotropic viruses types 1 and 2 in the 21st century (A systematic review)

Журнал инфектологии
Human T-lymphotropic viruses types 1 and 2 (HTLV-1/2) (family Retroviridae, genus Deltaretrovirus), are due to their genomic organization capable of long persistence and latency in the human body.
P. V. Apanovich, E. A. Domonova, V. G. Akimkin   +2 more
doaj   +1 more source

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

Journal of the Chinese Chemical Society, EarlyView.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source

Clonality of HTLV-2 in natural infection.

PLoS Pathogens, 2014
Human T-lymphotropic virus type 1 (HTLV-1) and type 2 (HTLV-2) both cause lifelong persistent infections, but differ in their clinical outcomes. HTLV-1 infection causes a chronic or acute T-lymphocytic malignancy in up to 5% of infected individuals ...
Anat Melamed, Aviva D Witkover, Daniel J Laydon, Rachael Brown, Kristin Ladell, Kelly Miners, Aileen G Rowan, Niall Gormley, David A Price, Graham P Taylor, Edward L Murphy, Charles R M Bangham   +11 more
doaj   +1 more source

High Prevalence and Risk Factors for Infection with Human T-Lymphotropic Viruses 1 and 2 in the Municipality of Ananindeua, Pará, Northern Brazil

Viruses
This descriptive, observational, cross-sectional study evaluated HTLV-1 and HTLV-2 infections in Ananindeua, northern Brazil. Individuals were screened for anti-HTLV-1/2 using ELISA (Murex HTLV-I + II, DiaSorin).
Dara da Costa Soares, Felipe Teixeira Lopes, Gabriel dos Santos Pereira Neto, Luciana Cristina Coelho Pantoja Santos, Aline Cecy Rocha Lima, Bruno Sarmento Botelho, Isabella Nogueira Abreu, Felipe Bonfim Freitas, Ricardo Ishak, Izaura Maria Vieira Cayres Vallinoto, Antonio Carlos Rosário Vallinoto   +10 more
doaj   +1 more source

Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil

Memorias do Instituto Oswaldo Cruz, 2014
Human T-cell lymphotropic virus (HTLV) may impact the clinical course of tuberculosis (TB). Both infections are highly endemic in Brazil. The aim of this study was to assess the prevalence of HTLV-1/2 in TB patients in Central-West Brazil and to perform ...
Aline Garcia Kozlowski, Megmar Aparecida dos Santos Carneiro, Marcia Alves Dias de Matos, Sheila Araujo Teles, Joao Alves Araujo Filho, Koko Otsuki, Ana Carolina Paulo Vicente, Regina Maria Bringel Martins   +7 more
doaj   +1 more source