Epidemiological analysis of HTLV-1 and HTLV-2 infection among different population in Central China. [PDF]
PLoS ONE, 2013 BACKGROUND: HTLV-1 and HTLV-2 are retroviruses linked etiologically to various human diseases, and both of them can be transmitted by vertical route, sexual intercourse, blood transfusion and intravenous drug use.
Yunyun Ma +9 more
doaj +2 more sources
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology
, 2015 Human T-cell leukemia viruses type 1 and 2 (HTLV-1 and HTLV-2) share a common genetic organization, expression strategy and ability to infect and immortalize T-cells in vitro; however, HTLV-1 and HTLV-2 are strikingly different in terms of clinical ...
Francoise Bex +3 more
core +4 more sources
Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected Subjects [PDF]
Viruses, 2016 Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of ...
Benjamin Usadi +5 more
doaj +2 more sources
Novel perspectives on antisense transcription in HIV-1, HTLV-1, and HTLV-2. [PDF]
Front Microbiol, 2022 The genome of retroviruses contains two promoter elements (called long terminal repeat or LTR) at the 5′ and 3′ end of their genome. Although the expression of retroviral genes generally depends on the promoter located in the 5′ LTR, the 3′ LTR also has promoter activity responsible for producing antisense transcripts.
Lin E, Panfil AR, Sandel G, Jain P.
europepmc +4 more sources
Comparison of the Genetic Organization, Expression Strategies and Oncogenic Potential of HTLV-1 and HTLV-2. [PDF]
Leukemia Research and Treatment, 2012 Human T cell leukemia virus types 1 and 2 (HTLV-1 and HTLV-2) are genetically related complex retroviruses that are capable of immortalizing human T-cells in vitro and establish life-long persistent infections in vivo.
CAVALLARI, ILARIA +11 more
core +6 more sources
Prevalence of Human T-Lymphotropic Viruses 1 and 2 in Individuals Infected with Hepatitis C Virus in Belém do Pará, Brazil [PDF]
Tropical Medicine and Infectious DiseaseCoinfection between hepatitis C virus (HCV) and human T-lymphotropic virus 1/2 (HTLV-1/2) remains poorly investigated in the Northern Region of Brazil despite its clinically important condition. The objective of this study was to determine the prevalence
Renata Santos de Sousa +19 more
doaj +2 more sources
Neurological Signs and Symptoms in Human T-Lymphotropic Viruses 1 and 2 Infected Patients Living in the Amazon Region, Northern Brazil [PDF]
VirusesHTLV-1 and HTLV-2 infections are associated with various neurological manifestations, particularly HTLV-1-associated myelopathy (HAM). This descriptive, cross-sectional observational study aimed to investigate and analyze the neurological manifestations ...
Giovani Camelo do Nascimento +11 more
doaj +2 more sources
A Panel of Eight miRNAs Is Deregulated in HTLV-2 Infected PBMCs and BJABGu Cell Line. [PDF]
Int J Mol Sci, 2022 Despite human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 being retroviruses closely related at a genomic level, HTLV-2 differs from HTLV-1 in terms of pathogenicity in both single infection and coinfection contexts. Moreover, the HTLV-2 association with clinical outcomes is still debated and several mechanisms underlying HTLV-2 infection remain ...
Pilotti E +8 more
europepmc +3 more sources
Viruses, 2022 Human T-cell lymphotropic virus type 1 and 2 (HTLV-1/2) screening is not mandatory in Spanish blood banks. In Catalonia, selective screening was introduced in 2008, followed by universal screening in 2011.
Maria Piron +8 more
doaj +1 more source
Frontiers in Microbiology, 2022 The human T-lymphotropic virus 1 (HTLV-1) and 2 (HTLV-2) can be transmitted between humans by mechanisms associated with horizontal and vertical routes.
Aldemir Branco Oliveira-Filho +16 more
doaj +1 more source