Results 11 to 20 of about 34,765 (207)

HTLV-2 Encoded Antisense Protein APH-2 Suppresses HIV-1 Replication. [PDF]

Viruses, 2021
Antisense protein of Human T-cell Leukemia Virus Type 2 (HTLV-2), also called APH-2, negatively regulates the HTLV-2 and helps the virus to maintain latency via scheming the transcription. Despite the remarkable occurrence of HTLV-2/HIV-1 co-infection, the role of APH-2 influencing HIV-1 replication kinetics is poorly understood and needs investigation.
Londhe R, Kulkarni S.
europepmc   +5 more sources

Neurological Signs and Symptoms in Human T-Lymphotropic Viruses 1 and 2 Infected Patients Living in the Amazon Region, Northern Brazil [PDF]

Viruses
HTLV-1 and HTLV-2 infections are associated with various neurological manifestations, particularly HTLV-1-associated myelopathy (HAM). This descriptive, cross-sectional observational study aimed to investigate and analyze the neurological manifestations ...
Giovani Camelo do Nascimento, Lucas Thiago Ferreira Monteiro, Hemengella Karyne Alves Oliveira, Márcio Yutaka Tsukimata, Bianca Lumi Inomata da Silva, Aline Cecy Rocha Lima, Rodrigo Borges de Oliveira, Gabriel dos Santos Pereira Neto, Eduardo Leitão Maia, Ricardo Ishak, Antonio Carlos Rosário Vallinoto, Izaura Maria Vieira Cayres Vallinoto   +11 more
doaj   +2 more sources

Novel perspectives on antisense transcription in HIV-1, HTLV-1, and HTLV-2. [PDF]

Front Microbiol, 2022
The genome of retroviruses contains two promoter elements (called long terminal repeat or LTR) at the 5′ and 3′ end of their genome. Although the expression of retroviral genes generally depends on the promoter located in the 5′ LTR, the 3′ LTR also has promoter activity responsible for producing antisense transcripts.
Lin E, Panfil AR, Sandel G, Jain P.
europepmc   +4 more sources

HTLV-1/2 Infection in Blood Donors from a Non-Endemic Area (Catalonia, Spain) between 2008 and 2017: A 10-Year Experience

Viruses, 2022
Human T-cell lymphotropic virus type 1 and 2 (HTLV-1/2) screening is not mandatory in Spanish blood banks. In Catalonia, selective screening was introduced in 2008, followed by universal screening in 2011.
Maria Piron, Fernando Salvador, Estrella Caballero, Adrián Sánchez-Montalvá, Marta Bes, Natàlia Casamitjana, Lluís Puig, Israel Molina, Silvia Sauleda   +8 more
doaj   +1 more source

Spread of Human T-Lymphotropic Virus 1 and 2 Among Relatives of People Who Use Illicit Drugs in Northern Brazil

Frontiers in Microbiology, 2022
The human T-lymphotropic virus 1 (HTLV-1) and 2 (HTLV-2) can be transmitted between humans by mechanisms associated with horizontal and vertical routes.
Aldemir Branco Oliveira-Filho, Aldemir Branco Oliveira-Filho, Paula Cristina Rodrigues Frade, Ricardo Roberto de Souza Fonseca, Leila Sawada, Luísa Caricio Martins, Luísa Caricio Martins, Luiz Fernando Almeida Machado, Luiz Fernando Almeida Machado, Antonio Carlos Rosário Vallinoto, Antonio Carlos Rosário Vallinoto, Ricardo Ishak, Ricardo Ishak, José Alexandre Rodrigues de Lemos, Benedikt Fischer, Benedikt Fischer, Emil Kupek   +16 more
doaj   +1 more source

Neurological Aspects of HIV-1/HTLV-1 and HIV-1/HTLV-2 Coinfection. [PDF]

Pathogens, 2020
Simultaneous infection by human immunodeficiency viruses (HIV) and human T-lymphotropic viruses (HTLV) are not uncommon since they have similar means of transmission and are simultaneously endemic in many populations. Besides causing severe immune dysfunction, these viruses are neuropathogenic and can cause neurological diseases through direct and ...
Araujo AQ.
europepmc   +5 more sources

Immunological characteristics of Spanish IDUs infected with HTLV-2 and HIV-1 [PDF]

Retrovirology, 2011
Background HTLV-2 infection has been detected in injecting drug users (IDUs) in Spain, who often are coinfected with HCV and HIV-1. It has been reported that HCV infection increases the immune activation of HIV-1-infected patients. Our objective was to analyze how HTLV-2 infection affects T-cell activation and other immunological parameters such as ...
Maria Abad, Fernando Dronda, Ana Moreno, Maria J Perez-Elias, Ester Dominguez, Santiago Moreno, Alejandro Vallejo   +6 more
core   +4 more sources

Anti-HTLV-1/2 IgG Antibodies in the Breastmilk of Seropositive Mothers

Microorganisms, 2021
Background: HTLV-1/2 mother-to-child transmission (MTCT) is an important route for the maintenance of HTLV-1/2 within populations and disproportionally contributes to the burden of HTLV-1-associated diseases.
Carolina Rosadas, Timothy Woo, Jana Haddow, Aileen Rowan, Graham P. Taylor   +4 more
doaj   +1 more source

HTLV-1 and HTLV-2 infections significantly alter small RNA expression in asymptomatic carriers. [PDF]

Front Med (Lausanne)
IntroductionThis study investigates the impact of HTLV-2 infection on small RNA (sRNA) expression profiles, building on previous findings related to HTLV-1.MethodsUsing Illumina Massive Parallel Sequencing, we analyzed sRNA profiles from asymptomatic HTLV-1 and HTLV-2 infected individuals and healthy controls.ResultsOur results reveal significant ...
Fernandes LA, Folgosi VÂ, Pessôa R, Assone T, Victor JR, Casseb J, de Oliveira ACP, Nukui Y, da Silva Duarte AJ, Sanabani SS.   +9 more
europepmc   +4 more sources

Silencers of HTLV-1 and HTLV-2: the pX-encoded latency-maintenance factors. [PDF]

Retrovirology, 2019
Of the members of the primate T cell lymphotropic virus (PTLV) family, only the human T-cell leukemia virus type-1 (HTLV-1) causes disease in humans-as the etiological agent of adult T-cell leukemia/lymphoma (ATLL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other auto-inflammatory disorders.
Harrod R.
europepmc   +5 more sources