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IntroductionUnderstanding of human T-lymphotropic virus (HTLV) remains largely based on epidemiologic and clinical data from endemic areas. Globalization has resulted in migration of persons living with HTLV (PLHTLV) from endemic to non-endemic areas ...
Margery Gang +4 more
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Background Human T-lymphotropic virus type 4 (HTLV-4) is a new deltaretrovirus recently identified in a primate hunter in Cameroon. Limited sequence analysis previously showed that HTLV-4 may be distinct from HTLV-1, HTLV-2, and HTLV-3, and their simian ...
Wolfe Nathan D +11 more
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Prevalence and risk factor analysis for HIV/HTLV 1/2 coinfection in Paraíba state, Brazil
Introduction: Human T-lymphotropic virus (HTLV) 1 and 2 infections can lead to neurological diseases, mainly in HIV/HTLV 1 coinfected. Furthermore, HTLV 1 infection in HIV/AIDS patients has also been associated with AIDS progression.
Marcela Santos de Souza +6 more
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Analysis of temporal expression of HTLV-2 reveals similarities and functional differences from HTLV-1 [PDF]
In the present study, we developed a robust splice site-specific real-time RT-PCR method to quantitate all HTLV-2 transcripts. Results of this analysis conducted on three different infected cell lines (HTLV-2A Mo-T , C344 and HTLV-2B BJAB-Gu) showed that
Bender Cecilia +23 more
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HTLV infection in Brazil’s second-largest indigenous reserve
Human T-lymphotropic viruses 1 and 2 (HTLV-1/2) have a worldwide distribution. HTLV-1 has been associated with several diseases, including an aggressive malignant disease known as adult T-cell leukemia/lymphoma and a chronic inflammatory neurological ...
Carolina Amianti +12 more
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In the present work, we developed and evaluated the performance of a new flow cytometry-based single platform, referred to as “FC-Duplex IgG1 (HTLV-1/2)”, for universal and differential serodiagnosis of HTLV-1/2 infection. The proposed technology employs
Luciene Pimenta de Paiva +18 more
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Laboratory diagnosis of human T-lymphotropic viruses (HTLV) 1 and 2 infection is performed by serological screening and further confirmation with serological or molecular assays.
Yago Gomes +8 more
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Co-infections of hepatitis C virus (HCV) and either human immunodeficiency virus type 1 (HIV-1), human T-cell lymphotropic virus type 1 (HTLV-1) or type 2 (HTLV-2) have been described as having an impact on HCV viremia and subsequent disease progression.
Fabiana Aparecida Alves +4 more
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Presence of a functional but dispensable Nuclear Export Signal in the HTLV-2 Tax protein [PDF]
Abstract Background Human T-cell leukemia virus type 1 and type 2 are related human retroviruses. HTLV-1 is the etiological agent of the Adult T-cell Leukemia/Lymphoma and of the Tropical Spastic Paraparesis/HTLV-1 Associated Myelopathy, whereas, HTLV-2 infection has not been formally associated with any T-cell ...
Chevalier, S.A. +5 more
openaire +4 more sources
HIGHLIGHTS ON DISTINCTIVE STRUCTURAL AND FUNCTIONAL PROPERTIES OF HTLV TAX PROTEINS.
Human T-cell Leukemia Viruses (HTLVs) are complex human retroviruses of the Deltaretrovirus genus. Four types have been identified thus far, with HTLV-1 and HTLV-2 much more prevalent than HTLV-3 or -4 .
Maria Grazia Romanelli +6 more
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