Results 81 to 90 of about 17,692,958 (217)

Strengths, Weaknesses, Opportunities and Threats (SWOT) Analysis of the Implementation of Public Health Policies on HTLV-1 in Brazil

open access: yesFrontiers in Medicine, 2022
Human T lymphotropic virus 1 (HTLV-1) is a public health issue for most countries and imposes important consequences on patients' health and socioeconomic status. Brazil is one of the global leaders of the public health response to these viruses.
Angelica Espinosa Miranda   +7 more
doaj   +1 more source

UK Infected Blood Inquiry–An Historical Appraisal

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction This appraisal considers the 2018 UK Infected Blood Inquiry and its Report (2024) in the context of the history of haemophilia treatment developments over the past fifty‐five years, and the tragic impacts of the AIDS pandemic. Aim The paper appraises the conduct and findings of the IBI and its Report in relation to HIV and AIDS ...
Christopher A. Ludlam
wiley   +1 more source

Functional interactions of the Tax and p13 proteins of Human T-cell Leukemia Virus Type I [PDF]

open access: yes, 2013
Human T-cell leukemia virus type 1 (HTLV-1) establishes a lifelong persistent infection in humans. Approximately 3% of the infected individuals will develop adult T-cell leukemia/lymphoma (ATLL), an aggressive malignancy of mature CD4+ T-cells. The viral
Manicone, Mariangela
core  

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala   +14 more
wiley   +1 more source

HTLV-1c proviral load compared between asymptomatic subjects, bronchiolitis/bronchitis and bronchiectasis.

open access: yes, 2018
Subjects with chronic airways disease were examined by chest high resolution computed tomography. Median (IQR) HTLV-1c pVL for subjects with bronchiolitis/bronchitis (2.69 (0.82, 3.43) log10 copies per 105 PBL) and bronchiectasis (2.69 (1.57, 3.49) log10
Charles Bangham (3429920)   +7 more
core   +1 more source

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

open access: yesImmunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu   +24 more
wiley   +1 more source

HIV-1/HTLV Co-Infection: a Survey of Molecular Basis with Clinical Studies [PDF]

open access: yesPatient Safety and Quality Improvement Journal, 2017
Human immunodeficiency virus type-1 (HIV–1) and human T-cell leukemia virus (HIV-1/HTLV) co-infection is a serious health problem worldwide, especially in endemic areas and vulnerable subjects like intravenous drug abusers.
Marzieh Saberi, Ashraf Tavanaii sani
doaj   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

open access: yesJournal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag   +6 more
wiley   +1 more source

Mimicry between HTLV-I and myelinbasicprotein: No response in HTLV-I-associatedmyelopathypatients

open access: yes, 1992
The reactivity to a peptide from the HTLV-I polyprotein (FKLPGLNSR) and a similar sequence from myelinbasicprotein (MBP) (FKLGGRDSR) was examined in relation to the proposal that mimicry of MBP by HTLV-I could be involved in autoimmune responses in HTLV ...
Carnegie, P.R.   +6 more
core   +1 more source

HTLV-1/-2 and HIV-1 Co-infections: Retroviral Interference On Host Immune Status

open access: yesFrontiers in Microbiology, 2013
The human retroviruses HIV-1 and HTLV-1/HTLV-2 share similar routes of transmission but cause significantly different diseases. In this review we have outlined the immune mediated mechanisms by which HTLVs affect HIV-1 disease in co-infected hosts ...
Elisabetta ePilotti   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy