Sabida la importante seroprevalencia en la Isla de Margarita para el HIV-1 nos propusimos conocer la seroprevalencia de HTLV-I/II en muestras de grupos epidemiologicamente importantes en su transmisión.
E. Castro de Batänjer +1 more
doaj +1 more source
Expansion in CD39(+) CD4(+) Immunoregulatory T Cells and Rarity of Th17 Cells in HTLV-1 Infected Patients Is Associated with Neurological Complications [PDF]
HTLV-1 infection is associated with several inflammatory disorders, including the neurodegenerative condition HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). It is unclear why a minority of infected subjects develops HAM/TSP.
A El Hed +95 more
core +4 more sources
Mapping genetic interactions in cancer: a road to rational combination therapies. [PDF]
The discovery of synthetic lethal interactions between poly (ADP-ribose) polymerase (PARP) inhibitors and BRCA genes, which are involved in homologous recombination, led to the approval of PARP inhibition as a monotherapy for patients with BRCA1/2 ...
Krogan, Nevan J, Tutuncuoglu, Beril
core
Seroprevalence of HTLV-1 and HTLV-2 amongst mothers and children in Malawi within the context of a systematic review and meta-analysis of HTLV seroprevalence in Africa [PDF]
OBJECTIVES: Human T‐lymphotropic virus (HTLV)‐1 causes T‐cell leukaemia and myelopathy. Together with HTLV‐2, it is endemic in some African nations. Seroprevalence data from Malawi are scarce, with no reports on associated disease incidence.
Bland, M +7 more
core +1 more source
HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population
OBJECTIVE: Blood donors in Brazil have been routinely screened for HTLV-I/II since 1993. A study was performed to estimate the prevalence of HTLV-I/II infection in a low risk population and to better understand determinants associated with seropositivity.
Soares Bernadette Catalan +2 more
doaj +3 more sources
Background and Objectives: Human T-cell lymphotropic virus type-I (HTLV-I) infection is considered as a public health challenge in endemic areas. The virus is associated with severe diseases, such as adult T-cell leukemia/lymphoma, and HTLV-I-associated ...
Mahtab Maghsudlu +2 more
doaj +1 more source
Assessment of HTLV-I proviral load, HIV viral load and CD4 T cell count in infected subjects; with an emphasis on viral replication in co-infection [PDF]
Objective(s): HTLV-I and HIV virus quantification is an important marker for assessment of virus activities. Since there is a direct relationship between the number of virus and disease progression, HTLV- I and HIV co-infection might have an influence on
Hossein Rahimi +4 more
doaj
A comparison between numerical solutions to fractional differential equations: Adams-type predictor-corrector and multi-step generalized differential transform method [PDF]
In this note, two numerical methods of solving fractional differential equations (FDEs) are briefly described, namely predictor-corrector approach of Adams-Bashforth-Moulton type and multi-step generalized differential transform method (MSGDTM), and then
Ahrabi, Sima Sarv, Momenzadeh, Alireza
core +2 more sources
The roles of acquired and innate immunity in human T-cell leukemia virus type 1-mediated diseases
Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis in small subsets of HTLV-1-carriers.
Mari eKannagi +4 more
doaj +1 more source
Background Human T-cell leukemia virus type I (HTLV-I) has efficiently adapted to its host and establishes a persistent infection characterized by low levels of viral gene expression and slow proliferation of HTLV-I infected cells over decades.
Bai XueTao +3 more
doaj +1 more source

