Results 61 to 70 of about 21,965 (226)

HTLV‐1 Tax Reshapes the DNA‐Binding Pattern of Transcription Factor IRF4 and Disrupts Host Gene Regulation

open access: yesCancer Science, Volume 117, Issue 5, Page 1497-1509, May 2026.
Proteomic mapping of Tax complexes in HTLV‐1–infected T‐cells identified IRF4 as a Tax interactor. Chromatin profiling showed Tax reprograms IRF4 occupancy with H3K27ac gains at super‐enhancers; Tax–IRF4 co‐expression altered chromatin accessibility and transcription, and ATL‐associated IRF4 mutants partially phenocopied these changes. ABSTRACT Human T‐
Shu Tosaka   +4 more
wiley   +1 more source

Risk Factors for Human T Cell Lymphotropic Virus Type I among Injecting Drug Users in Northeast Brazil: Possibly Greater Efficiency of Male to Female Transmission

open access: yesMemorias do Instituto Oswaldo Cruz, 1999
It was observed in the city of Salvador, State of Bahia, the highest seroprevalence of human T cell lymphotropic virus type 1 (HTLV-I) infection in Brazil as demonstrated by national wide blood bank surveys.
Inês Dourado   +3 more
doaj   +1 more source

Effect of pulsed methylprednisolone on pain, in patients with HTLV-1-associated myelopathy [PDF]

open access: yes, 2016
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an immune mediated myelopathy caused by the human T-lymphotropic virus type 1 (HTLV-1). The efficacy of treatments used for patients with HAM/TSP is uncertain.
Adonis, A   +8 more
core   +1 more source

Deceased donor ABO discrepancy due to a rare AwB subgroup: Implications for organ allocation

open access: yesTransfusion, Volume 66, Issue 5, Page 952-956, May 2026.
Abstract Background Accurate ABO determination is critical for safe deceased donor organ allocation. Weak or variant ABO subgroups may not be reliably detected by routine serologic testing, especially under urgent conditions or following transfusion. Such limitations can result in discrepant ABO assignments with potential implications for transplant ...
Sara O. Dionne   +3 more
wiley   +1 more source

Human T-Lymphotropic viruses evolution possibly explained by primate deltaretrovirus geographical segregation [PDF]

open access: yes, 2008
The primate T cell lymphotropic virus group comprises pathogenic and apathogenic agents found in human and simian hosts. Up to date, three types of the simian T cell lymphotropic virus/STLV and four types of the human T cell lymphotropic virus/HTLV have ...
Casseb, Jorge Simão do Rosário   +1 more
core  

Functional investigation of the RHD gene promoter: Molecular changes are rarely responsible for variant D phenotype in Thai donors

open access: yesTransfusion, Volume 66, Issue 5, Page 957-963, May 2026.
Abstract Background While modern technology is increasingly available to identify efficiently the molecular alterations responsible for variant phenotype, a subset of samples still escapes those analyses. In addition to the promoter region, two intronic regions containing GATA1 binding sites within the RHD gene locus were recently shown to modulate the
Caroline Bénech   +2 more
wiley   +1 more source

Efficiency of indirect immunofluorescence assay as a confirmatory test for the diagnosis of human retrovirus infection (HIV-1 and HTLV-I/II) in different at risk populations

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1999
We compared the indirect immunofluorescence assay (IFA) with Western blot (Wb) as a confirmatory method to detect antibodies anti retrovirus (HIV-1 and HTLV-I/II).
GASTALDELLO René   +4 more
doaj  

Prevalence of anxiety, depression and quality of life in HTLV-1 infected patients [PDF]

open access: yes
The HAM/TSP caused by HTLV-1 infection usually affects patients to disabling states, and\ud sometimes can lead them to paraplegia presenting symptoms of depression and anxiety, impacting\ud on quality of life.
Capitão, Claudio Garcia   +5 more
core   +1 more source

Retroviral matrix and lipids, the intimate interaction [PDF]

open access: yes, 2011
International audienceRetroviruses are enveloped viruses that assemble on the inner leaflet of cellular membranes. Improving biophysical techniques has recently unveiled many molecular aspects of the interaction between the retroviral structural protein ...
Delphine Muriaux, Elise Hamard-Peron
core   +5 more sources

HTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progression

open access: yesMolecular Cancer, 2010
Background Human T-cell leukemia virus type I (HTLV-I) has efficiently adapted to its host and establishes a persistent infection characterized by low levels of viral gene expression and slow proliferation of HTLV-I infected cells over decades.
Bai XueTao   +3 more
doaj   +1 more source

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