Results 71 to 80 of about 50,432 (228)

HTLV-1 Tax mutants that do not induce Garrest are disabled in activating the anaphase promoting complex-1

open access: yes, 2011
Copyright information:Taken from "HTLV-1 Tax mutants that do not induce Garrest are disabled in activating the anaphase promoting complex"http://www.retrovirology.com/content/4/1/35Retrovirology 2007;4():35-35.Published online 29 May 2007PMCID:PMC1894815.
Randall Merling (75706)   +6 more
core   +1 more source

Cost-effectiveness of human T-cell leukemia virus type 1 (HTLV-1) antenatal screening for prevention of mother-to-child transmission.

open access: yesPLoS Neglected Tropical Diseases, 2023
BackgroundHuman T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL) and HTLV-1-associated myelopathy-tropical spastic paraparesis (HAM/TSP) with a poor prognosis.
Akiko Kowada
doaj   +1 more source

Human Cortical Neural Progenitor Cells

open access: yes
Cell Proliferation, EarlyView.
An‐Xin Wang   +29 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, Volume 20, Issue 9, Page 2296-2322, September 2026.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses

open access: yesCell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo   +4 more
wiley   +1 more source

Oral Relapsing Lymphomatoid Papulosis: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Lymphomatoid papulosis (LyP) is a CD30+ T‐cell lymphoproliferative disorder rarely involving mucosa, where it may mimic aggressive lymphomas. This case highlights its chronic relapsing course, diagnostic challenges with ALK‐negative anaplastic T‐cell lymphoma, and the importance of long‐term follow‐up despite a favorable prognosis.
A. Bitton   +7 more
wiley   +1 more source

Functional Loss of the HTLV-I Tax Protein Encoded by Variant Proviruses in Infected Individuals. [PDF]

open access: yes, 1998
Accumulating evidence has indicated the presence of HTLV-I quasispecies in infected individuals. To elucidate their biological consequences, we amplified the whole Tax open reading frame (ORF) of HTLV-I proviruses by nested PCR from six infected ...
Yamashita-Futsuki, Izumi   +4 more
core  

Anemia as a Public Health Issue in Mashhad, Iran: Evidence from the First Population-Based Study

open access: yesActa Medica Iranica, 2015
Anemia is one of the main conditions that impose an adverse impact on the socioeconomic state of any country; however, evidence on the prevalence of anemia is scant in Northeastern Iran.
Iman Eftekharzadeh-Mashhadi   +4 more
doaj  

Prevalence of Human T-lymphotropic virus type 1 and 2 among blood donors in Manaus, Amazonas State, Brazil

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2017
Introduction: Human T-lymphotropic virus type 1 and 2 (HTLV-1/2) is endemic in Brazil, but few studies have investigated the seroprevalence of HTLV and its subtypes among blood donors in the capital city Manaus, Amazonas State, Brazil.
Márcia Poinho EncarnaçÃo de Morais   +5 more
doaj   +1 more source

The suppressor of cytokine signaling 3 regulates glioma stem cell maintenance and immune microenvironment through signal transducer and activator of transcription 3 signaling

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
We found that SOCS3 deficiency activates STAT3 to enhance glioma stem cell (GSC) stemness and survival. We demonstrated that IL‐6 rescues STAT3 signaling and reverses SOCS3‐mediated tumor suppression. We revealed that SOCS3‐low GSCs exhibit enriched p53 and JAK‐STAT pathway activity. This study provides new mechanistic insights into SOCS3‐STAT3 axis in
Jingtao Wang   +5 more
wiley   +1 more source

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