Results 41 to 50 of about 13,707,864 (242)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Together, leukemia and lymphoma account for 38.7% of newly diagnosed pediatric cancer cases in the United States each year. Many caregivers utilize online resources to inform medical health decisions. Understanding the readability of these materials is critical to ensuring comprehensible patient education.
Chloe Strege +6 more
wiley +1 more source
Web Performance Characteristics of HTTP/2 and Comparison to HTTP/1.1 [PDF]
, 2018 The HTTP/1.1 protocol has long been a staple on the web, for both pages and apps. However, it has started to show its age, especially with regard to page load performance and the overhead it entails due to its use of multiple underlying connections. Its successor, the newly standardized HTTP/2, aims to improve the protocol’s performance and reduce its ...
Robin Marx +4 more
openaire +2 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Радіоелектронні і комп'ютерні системиThe subject matter of this article is the methods to detect distributed denial-of-service (DDoS) attacks at the Hypertext Transfer Protocol (HTTP) level with the purpose of justifying the requirements for creating software capable of identifying ...
Arkadii Kravchuk, Mykola Onai
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A Relational Learning Approach to Structure-Activity Relationships in Drug Design Toxicity Studies
Journal of Integrative Bioinformatics, 2011 It has been recognized that the development of new therapeutic drugs is a complex and expensive process. A large number of factors affect the activity in vivo of putative candidate molecules and the propensity for causing adverse and toxic effects is ...
Camacho Rui +6 more
doaj +1 more source
Desarrollo del nuevo paradigma educativo. Más allá de la formación online: la formación en red
RIED: Revista Iberoamericana de Educación a Distancia, 2002 En este artículo tratamos de analizar en primer lugar las ventajas que ha supuesto la integración de las Nuevas Tecnologías, sobre todo Internet y el correo electrónico, en la educación a distancia. Es lo que a se ha llamado e-learning o formación online.
Luis Ángel Fernández Hermana +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
HTTP/2.0 - The IETF is Phoning It In [PDF]
Queue, 2014 Bad protocol, bad politics.
openaire +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source