Results 41 to 50 of about 38,122,293 (284)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

ВЫБОР ВЕБ-ТЕХНОЛОГИИ ДЛЯ ИНТЕГРАЦИИ С ПЛАТФОРМОЙ «1С: ПРЕДПРИЯТИЯ 8»

open access: yesCifra: Информационные технологии и телекоммуникации
В статье разобраны способы интеграции платформы «1С: Предприятие 8» с веб-технологиями для создания альтернативного пользовательского интерфейса, разрешающего задачи, возникающие у предприятия: реализация интерфейса для работы сотрудников и разработка ...
Ширяев А.И.
doaj   +1 more source

Web Performance Characteristics of HTTP/2 and Comparison to HTTP/1.1 [PDF]

open access: yes, 2018
The HTTP/1.1 protocol has long been a staple on the web, for both pages and apps. However, it has started to show its age, especially with regard to page load performance and the overhead it entails due to its use of multiple underlying connections. Its successor, the newly standardized HTTP/2, aims to improve the protocol’s performance and reduce its ...
Robin Marx   +4 more
openaire   +3 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Developing information technology for evaluating and enhancing application-layer DDoS attack detection methods

open access: yesРадіоелектронні і комп'ютерні системи
The subject matter of this article is the methods to detect distributed denial-of-service (DDoS) attacks at the Hypertext Transfer Protocol (HTTP) level with the purpose of justifying the requirements for creating software capable of identifying ...
Arkadii Kravchuk, Mykola Onai
doaj   +1 more source

A Relational Learning Approach to Structure-Activity Relationships in Drug Design Toxicity Studies

open access: yesJournal of Integrative Bioinformatics, 2011
It has been recognized that the development of new therapeutic drugs is a complex and expensive process. A large number of factors affect the activity in vivo of putative candidate molecules and the propensity for causing adverse and toxic effects is ...
Camacho Rui   +6 more
doaj   +1 more source

HTTP/2.0 - The IETF is Phoning It In [PDF]

open access: yesQueue, 2014
Bad protocol, bad politics.
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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