Results 51 to 60 of about 38,122,293 (284)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Boas práticas para a melhoria de desempenho de páginas web: um estudo sobre http/1.1 e http/2 [PDF]

open access: yes, 2018
A qualidade da experiência de navegação de um usuário está ligada diretamente à velocidade com a qual páginas da web são baixadas a partir dos servidores de hospedagem e, em seguida, exibidas no navegador.
Pereira, Léon Augusto de Araújo
core  

Desarrollo del nuevo paradigma educativo. Más allá de la formación online: la formación en red

open access: yesRIED: Revista Iberoamericana de Educación a Distancia, 2002
En este artículo tratamos de analizar en primer lugar las ventajas que ha supuesto la integración de las Nuevas Tecnologías, sobre todo Internet y el correo electrónico, en la educación a distancia. Es lo que a se ha llamado e-learning o formación online.
Luis Ángel Fernández Hermana   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Twenty Nineteen Web Almanac: HTTP Archive's Annual State of the Web Report

open access: yes, 2019
The Web Almanac is an annual state of the web report combining the expertise of the web community with the data and trends of the HTTP Archive. The Web Almanac is a project organized by HTTP Archive. HTTP Archive was started in 2010 by Steve Souders with
Pollard, Barry, HTTP Archive
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

http://handle.ncl.edu.tw/11296/ndltd/62060334960882376899

open access: yes, 2014
[[abstract]]The purpose of research investigates the present situation among Railway Tourism Attraction, Tourists’ Experiential Value and Revisiting Intention, and through questionnaire survey to understanding the tourists’ feeling.
http://handle.ncl.edu.tw/11296/ndltd/62060334960882376899
core  

HTTP 1.1 Versus HTTP 2: A Comparison

open access: yes, 2020
2015 hat die IETF eine neue HTTP-Version offiziell standardisiert. Basierend auf SPDY, setzt HTTP 2 seinen Schwerpunkt auf Verbesserung der Performanz und behebt das Head-of-Line Blocking Problem bei HTTP 1.1. Das neue Protokoll HTTP 2 verspricht kürzere
Jabr, Rukayah
core   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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