Results 61 to 70 of about 38,122,293 (284)

Una caza del tesoro para aprender la pronunciación del español

Foro de profesores de Español como Lengua Extranjera, 2012
El grupo Pronuncia bien surgió en el seno del Máster de Enseñanza de español einglés como L2/LE de la Universidad de Alicante bajo la dirección del profesor Xose A.Padilla.
Xose Padilla García, Elisa Gironzetti, Irene Martínez, Alberto Pastor   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Outcome of probing and syringing in congenital nasolacrimal duct obstruction at various age groups in a tertiary eye center in Western Nepal

Asian Journal of Medical Sciences, 2018
Background: Congenital nasolacrimal duct obstruction (CNLDO) is one of the commonest problems encountered in daily ophthalmology practice. Though probing and syringing is the mainstay of management of CNLDO, there is no clear guideline about the optimal ...
Koshal Shrestha , Binita Bhattarai , Laxmi Devi Manandhar , Salma KC Rai , Arniko Pandey , Shanti Gurung   +5 more
doaj   +1 more source

HTTP Evolution: A Survey of HTTP/1.1, HTTP/2, and HTTP/3 Protocol Design and Performance

International Journal of Advanced Research in Science Communication and Technology
The Hypertext Transfer Protocol (HTTP) is the foundational communication protocol of the World Wide Web, governing how data is transferred between clients and servers. Over the past three decades, HTTP has undergone significant evolution to meet the growing demands of modern web applications.
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Cervical cancer analysis: From burden to treatment

Asian Journal of Medical Sciences, 2018
Background: Cancer has emerged as huge epidemic over past two decades. There is a declining trend in the incidence of cervical cancer in the western world on the contrary in India we have observed that this disease is a great menace to a women’s health ...
Disha Tiwari , Kirti Srivastava , Dewesh Kishan, Manjari Shah   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Assessment of ecosystem services within the framework of general planning of urban areas

Наукові праці Лісівничої академії наук України, 2019
Based on the analysis of literary sources and master plans for cities development, the current state and level of the concept of ecosystem services implementation in the urban planning in Ukraine is revealed, and prospects for its integration and ...
Vasyl Yukhnovskyi , Olga Zibtseva
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source