Results 61 to 70 of about 13,356,633 (261)

New insights into genotype–phenotype correlation in individuals with different level of general non-specific reactivity of an organism

open access: yesJournal of Integrative Bioinformatics, 2016
The objective of the study was to investigate the genetic basis of general non-specific reactivity of an organism. Systematic search in PubMedCentral, PDB, KEGG and SNP databases identified a set of genes and their polymorphisms that can determine pain ...
Mulik Alexander   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

RapidEye e la banda Red Edge per la creazione di Mappe di Clorofilla

open access: yesGEOmedia, 2013
RapidEye è una costellazione satellitare unica nel campo dell’osservazione della terra dallo spazio; è infatti costituitada cinque satelliti artificiali eliosincroni allineati sulla stessa orbita e perfettamente identici che permettonol’acquisizione d ...
Fabiano Campo, Valerio De Luca
doaj   +2 more sources

Typology and classification as methods of categorization of green space

open access: yesНаукові праці Лісівничої академії наук України, 2018
The paper author analyses the typologies of green space and the classifications of parks of post-Soviet (Ukraine, Belorussia), European (UK), North American (USA, Canada), Asian (Japan, China, Singapore, Malaysia) countries and cities of Australia.
Vasyl Yukhnovskyi , Olga Zibtseva
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Standards for estimating the crown productivity of pine stands within the conditions of the Northern Steppe of Ukraine

open access: yesНаукові праці Лісівничої академії наук України, 2019
The biological productivity of forests is considered as their main characteristic, which determines the course of processes in forest ecosystems. It is used for ecologi-cal monitoring with the constant management of forestry.
Petro Lakyda, Viktoriia Lovynska
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Mathematical model of the pressing process of lightweight particleboards with the expanded polystyrene in content

open access: yesНаукові праці Лісівничої академії наук України, 2018
Assuming that the chip-polymer package overlaid by rotary-cut veneer has the form of a plate located between the press plates heated to a certain temperature, and applying the known laws of Fourier thermal conductivity and the equation of heat quantity ...
Pavlo Bekhta , Liubov Baizova
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy