Results 51 to 60 of about 4,651,731 (290)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Debate - The Trafficking Protocol and the Anti-Trafficking Framework: Insufficient to address exploitation

open access: yesAnti-Trafficking Review, 2015
The Trafficking Protocol[1] has shaped and advanced a global movement against human trafficking; notably through establishing a global definition and creating criminal justice remedies befitting an international crime.[2] Borne out of and including the ...
Kathryn Baer
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Effect of Network and Infrastructural Variables on SPDY's Performance [PDF]

open access: yes, 2014
HTTP is a successful Internet technology on top of which a lot of the web resides. However, limitations with its current specification, i.e. HTTP/1.1, have encouraged some to look for the next generation of HTTP.
Elkhatib, Yehia   +2 more
core   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Characterizing SPDY over High Latency Satellite Channels

open access: yesEAI Endorsed Transactions on Mobile Communications and Applications, 2014
The increasing complexity ofWeb contents and the growing diffusion of mobile terminals, which use wireless and satellite links to get access to the Internet, impose the adoption of more specialized protocols.
Luca Caviglione, Alberto Gotta
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Poor Man's Content Centric Networking (with TCP) [PDF]

open access: yes, 2011
A number of different architectures have been proposed in support of data-oriented or information-centric networking. Besides a similar visions, they share the need for designing a new networking architecture.
Budigere, K.   +3 more
core   +1 more source

Improving the Authentication with Built-In Camera Protocol Using Built-In Motion Sensors: A Deep Learning Solution

open access: yesMathematics, 2021
In this paper, we propose an enhanced version of the Authentication with Built-in Camera (ABC) protocol by employing a deep learning solution based on built-in motion sensors.
Cezara Benegui, Radu Tudor Ionescu
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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