Results 91 to 100 of about 191 (111)
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Phytomedicine
Huangkui capsule (HKC), a Chinese patent medicine, is clinically used for treating diabetic nephropathy. However, the core disease-specific biomarkers and targets of type 2 diabetic nephropathy (T2DN) and the therapeutic mechanism of HKC are not fully elucidated.This study aimed to investigate the therapeutic effects and underlying molecular mechanisms
XiJun Wang
exaly +3 more sources
Huangkui capsule (HKC), a Chinese patent medicine, is clinically used for treating diabetic nephropathy. However, the core disease-specific biomarkers and targets of type 2 diabetic nephropathy (T2DN) and the therapeutic mechanism of HKC are not fully elucidated.This study aimed to investigate the therapeutic effects and underlying molecular mechanisms
XiJun Wang
exaly +3 more sources
Journal of Ethnopharmacology, 2015
In traditional Chinese medicine (TCM), Abelmoschus manihot (L.) medic (AM) is a natural medicinal plant used for the treatment of inflammatory diseases. Recently, Huangkui capsule (HKC), a Chinese patent medicine extracted from AM, has been widely applied to the clinical therapy of renal fibrosis in patients with early diabetic nephropathy (DN ...
Shan-Mei Shen
exaly +3 more sources
In traditional Chinese medicine (TCM), Abelmoschus manihot (L.) medic (AM) is a natural medicinal plant used for the treatment of inflammatory diseases. Recently, Huangkui capsule (HKC), a Chinese patent medicine extracted from AM, has been widely applied to the clinical therapy of renal fibrosis in patients with early diabetic nephropathy (DN ...
Shan-Mei Shen
exaly +3 more sources
Journal of Ethnopharmacology
Huangkui Capsule (HKC) is a traditional Chinese medicinal preparation. Numerous clinical studies have reported that HKC has a good nephroprotection effect. The clinical application of cisplatin is greatly limited by its nephrotoxicity, and HKC shows promise in preventing cisplatin-induced nephrotoxicity (CIN).To evaluate the effectiveness of HKC in ...
Jian-Dong Zou, Qiong Wang
exaly +3 more sources
Huangkui Capsule (HKC) is a traditional Chinese medicinal preparation. Numerous clinical studies have reported that HKC has a good nephroprotection effect. The clinical application of cisplatin is greatly limited by its nephrotoxicity, and HKC shows promise in preventing cisplatin-induced nephrotoxicity (CIN).To evaluate the effectiveness of HKC in ...
Jian-Dong Zou, Qiong Wang
exaly +3 more sources
Integrative Medicine in Nephrology and Andrology, 2023
ABSTRACT Diabetic kidney disease (DKD), a severe and common microvascular complication of diabetes mellitus, has become a major cause of end-stage renal disease. Huangkui capsule (HKC) has been widely used to treat DKD. This meta-analysis aimed to provide high-quality evidence for the clinical application of HKC in DKD.
Yunling Geng +8 more
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ABSTRACT Diabetic kidney disease (DKD), a severe and common microvascular complication of diabetes mellitus, has become a major cause of end-stage renal disease. Huangkui capsule (HKC) has been widely used to treat DKD. This meta-analysis aimed to provide high-quality evidence for the clinical application of HKC in DKD.
Yunling Geng +8 more
openaire +1 more source
Current Gene Therapy, 2019
Objective: The objective of the research is to investigate the effects of Huangkui capsule on the expression of SPARC in the kidney tissues of diabetic nephropathy. Methods: SD rats were divided into three groups: normal control group, untreated DN group and HKC-treated DN group.
Xiaoyao, Yang +3 more
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Objective: The objective of the research is to investigate the effects of Huangkui capsule on the expression of SPARC in the kidney tissues of diabetic nephropathy. Methods: SD rats were divided into three groups: normal control group, untreated DN group and HKC-treated DN group.
Xiaoyao, Yang +3 more
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Renal protective effect and action mechanism of Huangkui capsule and its main five flavonoids
Journal of Ethnopharmacology, 2017The flower of Abelmoschus manihot (Linn.) Medicus (A. manihot), as a traditional Chinese Herbal medicine, was used widely in China with efficacy of inducing diuresis for treating strangurtia, and subdhing swelling and detoxicating. It has been reported that Huangkui capsule, prepared by the extract of the flower of A. manihot, can reduce the content of
Hong-Die, Cai +7 more
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[Clinical comprehensive evaluation of Huangkui Capsules in treatment of chronic kidney diseases].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022Based on Guidelines for the Management of Clinical Comprehensive Evaluation of Drugs(trial version 2021), this study aims to sort out the clinical evidence of Huangkui Capsules(HC) in the treatment of chronic kidney diseases in aspects of safety, effectiveness, economy, innovation, suitability, accessibility, and characteristics of traditional Chinese ...
Zhi-Fei, Wang +2 more
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Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2013
To Set up a method for determining the contents of the five flavonoids simultaneously in the HuangKui capsule and analyze their specific chromatograms.HPLC method was used. The analytical column was Thermo scientific Hypersil GOLD (250 mm x 4.6 mm, 5 microm).
Lin, Liu +5 more
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To Set up a method for determining the contents of the five flavonoids simultaneously in the HuangKui capsule and analyze their specific chromatograms.HPLC method was used. The analytical column was Thermo scientific Hypersil GOLD (250 mm x 4.6 mm, 5 microm).
Lin, Liu +5 more
openaire +1 more source
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2023
Meta-analysis and integrative bioinformatics were employed to comprehensively study the efficacy, safety, and mechanism of Huangkui Capsules in treating chronic kidney disease(CKD). CNKI, Wanfang, VIP, SinoMed, Cochrane Library, PubMed, EMbase, and Web of Science were searched for randomized controlled trial(RCT) of Huangkui Capsules for CKD from ...
Fu-Ping, Wang +4 more
openaire +1 more source
Meta-analysis and integrative bioinformatics were employed to comprehensively study the efficacy, safety, and mechanism of Huangkui Capsules in treating chronic kidney disease(CKD). CNKI, Wanfang, VIP, SinoMed, Cochrane Library, PubMed, EMbase, and Web of Science were searched for randomized controlled trial(RCT) of Huangkui Capsules for CKD from ...
Fu-Ping, Wang +4 more
openaire +1 more source