Results 101 to 110 of about 191 (111)
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Journal of Ethnopharmacology
Huangkui capsule (HK) has demonstrated significant efficacy in managing chronic kidney disease. Previous studies have shown that HK can alleviate kidney damage; however, the therapeutic effects of HK on tacrolimus-induced chronic nephrotoxicity (TCN) and the underlying molecular mechanisms remain unclear.To evaluate the effectiveness of HK in ...
Tao Pang +10 more
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Huangkui capsule (HK) has demonstrated significant efficacy in managing chronic kidney disease. Previous studies have shown that HK can alleviate kidney damage; however, the therapeutic effects of HK on tacrolimus-induced chronic nephrotoxicity (TCN) and the underlying molecular mechanisms remain unclear.To evaluate the effectiveness of HK in ...
Tao Pang +10 more
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[LC/MS guided approach to discovering nephroprotective substances from Huangkui capsule].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2017Objective: To discover the nephroprotective substances from Huangkui capsule. Methods: The components of Huangkui capsule were isolated by preparative liquid chromatography, and the active components were screened by LC/MS and identified. The adriamycine-injured HK-2 cells were treated with various active components with different concentrations, and ...
Tingting, Ma +3 more
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2021
To observe the multi-targeted therapeutic effects of Huangkui Capsules(HKC)on insulin resistance(IR)and urine microalbumin in the early diabetic kidney disease(DKD)patients. The case data from the 83 DKD patients at G2 and A2 stage were collected respectively and analyzed retrospectively.
Wei, Wu +11 more
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To observe the multi-targeted therapeutic effects of Huangkui Capsules(HKC)on insulin resistance(IR)and urine microalbumin in the early diabetic kidney disease(DKD)patients. The case data from the 83 DKD patients at G2 and A2 stage were collected respectively and analyzed retrospectively.
Wei, Wu +11 more
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China Journal of Chinese Materia Medica, 2012
Objective To explore the potential mechanisms of huangkui capsule (HKC), an extract from Abelmoschus manihot (AM), for ameliorating renal inflammatory injury by regulating p38 mitogen-activated protein kinase (MAPK) signaling pathway in rats with adriamycin-induced nephropathy (ADRN).
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Objective To explore the potential mechanisms of huangkui capsule (HKC), an extract from Abelmoschus manihot (AM), for ameliorating renal inflammatory injury by regulating p38 mitogen-activated protein kinase (MAPK) signaling pathway in rats with adriamycin-induced nephropathy (ADRN).
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013
To explore the potential mechanisms of huangkui capsule (HKC), an extract from Abelmoschus manihot (AM), for ameliorating renal inflammatory injury by regulating p38 mitogen-activated protein kinase (MAPK) signaling pathway in rats with adriamycin-induced nephropathy (ADRN).Nineteen Sprague-Dawley (SD) rats were randomly divided into three groups, the ...
Qing, Zhao +6 more
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To explore the potential mechanisms of huangkui capsule (HKC), an extract from Abelmoschus manihot (AM), for ameliorating renal inflammatory injury by regulating p38 mitogen-activated protein kinase (MAPK) signaling pathway in rats with adriamycin-induced nephropathy (ADRN).Nineteen Sprague-Dawley (SD) rats were randomly divided into three groups, the ...
Qing, Zhao +6 more
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Literature Analysis on Clinical Efficacy of Huangkui Capsule in Treating Diabetic Nephropathy
Traditional Chinese Medicine, 2020openaire +1 more source
Journal of Chromatography B
Huangkui capsule (HKC), a proprietary traditional Chinese medicine, has been used for decades to clinically treat chronic kidney diseases. Gut microbiota may mediate its metabolism, yet inadequate research on HKC’s in vivo metabolism hinders understanding of its pharmacodynamic basis.
Si-Min Li +7 more
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Huangkui capsule (HKC), a proprietary traditional Chinese medicine, has been used for decades to clinically treat chronic kidney diseases. Gut microbiota may mediate its metabolism, yet inadequate research on HKC’s in vivo metabolism hinders understanding of its pharmacodynamic basis.
Si-Min Li +7 more
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2015
To demonstrate the effects and mechanisms of Huangkui capsule (HKC) on renal fibrosis in rats with diabetic nephropathy (DN).Rats were randomly divided into 5 groups, the sham-operated group (Sham group, n = 5), the vehicle-given group (Vehicle group, n = 7), the low dose of HKC-treated group (L-HKC group, n = 7), the high dose of HKC-treated group (H ...
Zhi-min, Mao +6 more
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To demonstrate the effects and mechanisms of Huangkui capsule (HKC) on renal fibrosis in rats with diabetic nephropathy (DN).Rats were randomly divided into 5 groups, the sham-operated group (Sham group, n = 5), the vehicle-given group (Vehicle group, n = 7), the low dose of HKC-treated group (L-HKC group, n = 7), the high dose of HKC-treated group (H ...
Zhi-min, Mao +6 more
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