Results 81 to 90 of about 191 (111)
Abelmoschus manihot alleviates insulin resistance in diabetic kidney disease through attenuation of inflammation. [PDF]
BMC NephrolWei X +6 more
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Phytomedicine, 2022
Chronic glomerulonephritis (CGN) is a relatively common primary glomerular disease. Huangkui capsule (HKC) combined with angiotensin receptor blocker (ARB) for CGN is frequently used in clinical practice, however, there is still lack of high-quality evidence-based evidence and network pharmacology to clarify the therapeutic efficacy and pharmacological
Yao Dai, Heng Yang, Jiayue Yang
exaly +3 more sources
Chronic glomerulonephritis (CGN) is a relatively common primary glomerular disease. Huangkui capsule (HKC) combined with angiotensin receptor blocker (ARB) for CGN is frequently used in clinical practice, however, there is still lack of high-quality evidence-based evidence and network pharmacology to clarify the therapeutic efficacy and pharmacological
Yao Dai, Heng Yang, Jiayue Yang
exaly +3 more sources
Effects of HuangKui capsules on glibenclamide pharmacokinetics in rats
Journal of Ethnopharmacology, 2012The main components of HuangKui capsules' are the total flavonoids extracted from the flowers of Abelmoschus manihot L medic. They have been widely used to treat chronic glomerulonephritis, diabetic nephropathy and nephrotic syndrome. The combination of HuangKui capsules and glibenclamide is a possible therapy for patients with diabetes mellitus and ...
Zixiu Liu, Xiaojun Gao
exaly +3 more sources
Journal of Ethnopharmacology, 2021
Huangkui capsule (HKC), extracted from Abelmoschus manihot (L.) medic (AM), as a patent proprietary Chinese medicine on the market for approximately 20 years, has been clinically used to treat chronic glomerulonephritis. Renal fibrosis has been implicated in the onset and development of diabetic nephropathy (DN).
Li-Yuan, Gu +3 more
exaly +3 more sources
Huangkui capsule (HKC), extracted from Abelmoschus manihot (L.) medic (AM), as a patent proprietary Chinese medicine on the market for approximately 20 years, has been clinically used to treat chronic glomerulonephritis. Renal fibrosis has been implicated in the onset and development of diabetic nephropathy (DN).
Li-Yuan, Gu +3 more
exaly +3 more sources
Phytomedicine, 2023
Mitochondria is critic to tubulopathy, especially in diabetic kidney disease (DKD). Huangkui capsule (HKC; a new ethanol extract from the dried corolla of Abelmoschus manihot) has significant clinical effect on DKD. Previous studies have shown that HKC protects kidney by regulating mitochondrial function, but its mechanism is still unclear.
Shiqiao Peng, Kaiyue Wu
exaly +3 more sources
Mitochondria is critic to tubulopathy, especially in diabetic kidney disease (DKD). Huangkui capsule (HKC; a new ethanol extract from the dried corolla of Abelmoschus manihot) has significant clinical effect on DKD. Previous studies have shown that HKC protects kidney by regulating mitochondrial function, but its mechanism is still unclear.
Shiqiao Peng, Kaiyue Wu
exaly +3 more sources
Phytomedicine
The management of kidney diseases urgently needs additional therapeutic options. Encouraging evidence suggests the efficacy of Huangkui capsules (HKCs), a plant-derived traditional medicine, in treating various subtypes of nephropathy. However, current evidence is fragmented between clinical outcomes and mechanistic insights.This study synthesized ...
Tongtong Wu, Xueyin Chen, Shaonan Liu
exaly +3 more sources
The management of kidney diseases urgently needs additional therapeutic options. Encouraging evidence suggests the efficacy of Huangkui capsules (HKCs), a plant-derived traditional medicine, in treating various subtypes of nephropathy. However, current evidence is fragmented between clinical outcomes and mechanistic insights.This study synthesized ...
Tongtong Wu, Xueyin Chen, Shaonan Liu
exaly +3 more sources
Chromatographia, 2011
In this paper, ultra performance liquid chromatography (UPLC)–quadrupole-time-of-flight mass spectrometry (QTOF) with collision energy (MS E ) and MassFragment software were applied for fast separation and characterization of constituents in HuangKui Capsules (HKC).
Jianming Guo +2 more
exaly +2 more sources
In this paper, ultra performance liquid chromatography (UPLC)–quadrupole-time-of-flight mass spectrometry (QTOF) with collision energy (MS E ) and MassFragment software were applied for fast separation and characterization of constituents in HuangKui Capsules (HKC).
Jianming Guo +2 more
exaly +2 more sources
Journal of Ethnopharmacology, 2023
Huangkui capsule (HKC), a Chinese patent medicine, has been widely used in China as adjuvant therapy for chronic kidney disease (CKD). It displays superior anti-proteinuria efficacy than losartan in patients with CKD at stages 1-2, however, the mechanism of HKC alleviating proteinuria has not been well elucidated.This study aims to confirm the ...
Chengzhi Chai
exaly +3 more sources
Huangkui capsule (HKC), a Chinese patent medicine, has been widely used in China as adjuvant therapy for chronic kidney disease (CKD). It displays superior anti-proteinuria efficacy than losartan in patients with CKD at stages 1-2, however, the mechanism of HKC alleviating proteinuria has not been well elucidated.This study aims to confirm the ...
Chengzhi Chai
exaly +3 more sources
Phytomedicine
Diabetic kidney disease (DKD) is a critical microvascular complication of diabetes mellitus. As a clinical therapeutic drug for DKD, the treatment mechanism of Huangkui Capsules (HKC) has not been clarified, which affects its individualized medication for patients.
Mengwen Wang +2 more
exaly +3 more sources
Diabetic kidney disease (DKD) is a critical microvascular complication of diabetes mellitus. As a clinical therapeutic drug for DKD, the treatment mechanism of Huangkui Capsules (HKC) has not been clarified, which affects its individualized medication for patients.
Mengwen Wang +2 more
exaly +3 more sources
Journal of Ethnopharmacology
Huangkui capsule (HKC), a patent traditional Chinese medicine, has shown significant efficacy in managing chronic kidney disease (CKD), particularly diabetic nephropathy (DN). Previous studies have shown that HKC can alleviate kidney damage in DN. However, the exact mechanisms through which it exerts its effects remain unclear.This study aimed to ...
Xiaotong Yan
exaly +3 more sources
Huangkui capsule (HKC), a patent traditional Chinese medicine, has shown significant efficacy in managing chronic kidney disease (CKD), particularly diabetic nephropathy (DN). Previous studies have shown that HKC can alleviate kidney damage in DN. However, the exact mechanisms through which it exerts its effects remain unclear.This study aimed to ...
Xiaotong Yan
exaly +3 more sources