Results 131 to 140 of about 243,473 (347)

Hub gene associated with prognosis in bladder cancer is the noval therapeutic target

, 2023
Yuanqiao He
openalex   +1 more source

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu, Lina Guan, Baihetiya Tayier, Chen Yuan, Shangke Chen, Qi Shi, Yuming Mu   +6 more
wiley   +1 more source

Transcriptomics explores potential mechanisms for the development of Primary Sjogren’s syndrome to diffuse large B-cell lymphoma in B cells

BMC Immunology
Purpose Primary Sjogren's syndrome (pSS) is a prevalent autoimmune disease. The immune dysregulation it causes often leads to the development of diffuse large B-cell lymphoma (DLBCL) in clinical practice.
Yanan Xu, Jianxing Han, Ziyi Fan, Shufen Liang   +3 more
doaj   +1 more source

Agricultural management and plant selection interactively affect rhizosphere microbial community structure and nitrogen cycling. [PDF]

, 2019
BACKGROUND:Rhizosphere microbial communities are key regulators of plant performance, yet few studies have assessed the impact of different management approaches on the rhizosphere microbiomes of major crops.
Brisson, Vanessa L, Gaudin, Amélie CM, Kent, Angela D, Schmidt, Jennifer E   +3 more
core   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

Ontological theory for ontological engineering: Biomedical systems information integration [PDF]

, 2004
Software application ontologies have the potential to become the keystone in state-of-the-art information management techniques. It is expected that these ontologies will support the sort of reasoning power required to navigate large and complex ...
Ceusters, Werner, Fielding, James M., Simon, Jonathan, Smith, Barry   +3 more
core   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Chaperones as integrators of cellular networks: Changes of cellular integrity in stress and diseases

, 2008
Cellular networks undergo rearrangements during stress and diseases. In un-stressed state the yeast protein-protein interaction network (interactome) is highly compact, and the centrally organized modules have a large overlap.
Albanese, Albert, Almaas, Arita, Barabasi, Barabasi, Batada, Batada, Batagelj, Bertin, Bobula, Colizza, Csermely, Csermely, Csermely, Csermely, Derenyi, Ekman, Gasch, Goldberger, Guimerá, Han, Kim, Komurov, Korcsmaros, Korcsmáros, Lewandowska, Linding, Luscombe, Macario, Maslov, McAuley, McClellan, Ng, Palla, Papp, Pál, Ravasz, Rutherford, Sales-Pardo, Shorter, Song, Soti, Soti, Soti, Szabadkai, Szalay, Tanaka, Taxis, Vigh, Wang, Watts, Xu, Yu, Zhu   +54 more
core   +2 more sources

Identification of hub genes in triple-negative breast cancer by integrated bioinformatics analysis [PDF]

, 2021
Limin Wei, Xinyang Li, Ziming Wang, Yukun Wang, Ge Yao, Jiahao Fan, Xinshuai Wang   +6 more
openalex   +1 more source

Evaluating Cytocompatibility of Corynebacterium glutamicum‐poly Vinyl Alcohol Living Biomaterials for Ocular Use

Advanced Healthcare Materials, EarlyView.
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai, Lorely Garcia‐Sanchez, Maryam Amini, Lara Luana Teruel‐Enrico, Silke Siegrist, Aránzazu del Campo, Sara Trujillo   +6 more
wiley   +1 more source